Enzyme

Download
EC Tree
     3. Hydrolases
        3.1 Acting on ester bonds
            3.1.1 Carboxylic-ester hydrolases
ID:3.1.1.56
Description:Methylumbelliferyl-acetate deacetylase.
Alternative Name: Esterase D.
Cath: 3.40.50.1820;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 3.1.1.56
BRENDA Enzyme Link: BRENDA 3.1.1.56
KEGG Enzyme Link: KEGG3.1.1.56
BioCyc Enzyme Link: BioCyc 3.1.1.56
ExPASy Enzyme Link: ExPASy3.1.1.56
EC2PDB Enzyme Link: EC2PDB 3.1.1.56
ExplorEnz Enzyme Link: ExplorEnz 3.1.1.56
PRIAM enzyme-specific profiles Link: PRIAM 3.1.1.56
IntEnz Enzyme Link: IntEnz 3.1.1.56
MEDLINE Enzyme Link: MEDLINE 3.1.1.56
MSA:

3.1.1.56;

Phylogenetic Tree:

3.1.1.56;

Uniprot:
M-CSA:
RHEA:12208 4-methylumbelliferyl acetate + H2O = 4-methylumbelliferone + acetate + H(+)
RULE(radius=1) [*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:4]-[*:5].[OH2;+0:6]>>[*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:6].[*:5]-[OH;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Purification and cloning of a broad substrate specificity human liver carboxylesterase that catalyzes the hydrolysis of cocaine and heroin.Pindel EV, Kedishvili NY, Abraham TL, Brzezinski MR, Zhang J, Dean RA, Bosron WF1997 Jun 69169443
Esterase D: a new human polymorphism.Hopkinson DA, Mestriner MA, Cortner J, Harris H1973 Oct4768551