Enzyme

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     3. Hydrolases
        3.1 Acting on ester bonds
            3.1.1 Carboxylic-ester hydrolases
ID:3.1.1.59
Description:Juvenile-hormone esterase.
Alternative Name: acylhydrolase.
Methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate
JH esterase.
Prosite: PDOC00112;
PDB:
PDBScop

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.1.1.59
BRENDA Enzyme Link: BRENDA 3.1.1.59
KEGG Enzyme Link: KEGG3.1.1.59
BioCyc Enzyme Link: BioCyc 3.1.1.59
ExPASy Enzyme Link: ExPASy3.1.1.59
EC2PDB Enzyme Link: EC2PDB 3.1.1.59
ExplorEnz Enzyme Link: ExplorEnz 3.1.1.59
PRIAM enzyme-specific profiles Link: PRIAM 3.1.1.59
IntEnz Enzyme Link: IntEnz 3.1.1.59
MEDLINE Enzyme Link: MEDLINE 3.1.1.59
MSA:

3.1.1.59;

Phylogenetic Tree:

3.1.1.59;

Uniprot:
M-CSA:
RHEA:46916 H2O + juvenile hormone I = H(+) + juvenile hormone I carboxylate + methanol
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH3;+0:3].[OH2;+0:4]>>[*:1]-[OH;+0:2].[CH3;+0:3]-[OH;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Characterization of two major isoforms of juvenile hormone esterase from Trichoplusia ni (Lepidoptera).Jones G, Manczak M, Wozniak M, Ko'rrati R1993 Feb 137679289
Characterization of affinity-purified juvenile hormone esterase from the plasma of the tobacco hornworm, Manduca sexta.Venkatesh K, Abdel-Aal YA, Armstrong FB, Roe RM1990 Dec 152254326

RHEA:46912 H2O + juvenile hormone III = H(+) + juvenile hormone III carboxylate + methanol
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH3;+0:3].[OH2;+0:4]>>[*:1]-[OH;+0:2].[CH3;+0:3]-[OH;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Characterization of two major isoforms of juvenile hormone esterase from Trichoplusia ni (Lepidoptera).Jones G, Manczak M, Wozniak M, Ko'rrati R1993 Feb 137679289
Characterization of affinity-purified juvenile hormone esterase from the plasma of the tobacco hornworm, Manduca sexta.Venkatesh K, Abdel-Aal YA, Armstrong FB, Roe RM1990 Dec 152254326

RHEA:16393 H2O + juvenile hormone II = H(+) + juvenile hormone II carboxylate + methanol
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH3;+0:3].[OH2;+0:4]>>[*:1]-[OH;+0:2].[CH3;+0:3]-[OH;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction