Enzyme

Download
EC Tree
     3. Hydrolases
        3.1 Acting on ester bonds
            3.1.1 Carboxylic-ester hydrolases
ID:3.1.1.6
Description:Acetylesterase.
Alternative Name: C-esterase (in animal tissues).
Cath: 3.40.710.10; 2.40.128.130; 3.40.50.1110; 3.40.50.1820;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.

References

External Links

UniProtKB Enzyme Link: UniProtKB 3.1.1.6
BRENDA Enzyme Link: BRENDA 3.1.1.6
KEGG Enzyme Link: KEGG3.1.1.6
BioCyc Enzyme Link: BioCyc 3.1.1.6
ExPASy Enzyme Link: ExPASy3.1.1.6
EC2PDB Enzyme Link: EC2PDB 3.1.1.6
ExplorEnz Enzyme Link: ExplorEnz 3.1.1.6
PRIAM enzyme-specific profiles Link: PRIAM 3.1.1.6
IntEnz Enzyme Link: IntEnz 3.1.1.6
MEDLINE Enzyme Link: MEDLINE 3.1.1.6
MSA:

3.1.1.6;

Phylogenetic Tree:

3.1.1.6;

Uniprot:
M-CSA:
RHEA:12957 an acetyl ester + H2O = acetate + an aliphatic alcohol + H(+)
RULE(radius=1) [*:1]-[O;H0;+0:2]-[*;H0;+0:3].[OH2;+0:4]>>[*;H0;+0:3]-[OH;+0:4].[*:1]-[OH;+0:2]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Molecular characterization of human ABHD2 as TAG lipase and ester hydrolase.M NK, V B S C T, G K V, B CS, Guntupalli S, J S B2016 Aug27247428
Characterization and function of Mycobacterium tuberculosis H37Rv Lipase Rv1076 (LipU).Li C, Li Q, Zhang Y, Gong Z, Ren S, Li P, Xie J2017 Mar28164792
Mycobacterium tuberculosis rv1400c encodes functional lipase/esterase.Lin Y, Li Q, Xie L, Xie J2017 Jan27154903
Identification and Characterization of Lipase Activity and Immunogenicity of LipL from Mycobacterium tuberculosis.Cao J, Dang G, Li H, Li T, Yue Z, Li N, Liu Y, Liu S, Chen L201526398213
Characterization of LipN (Rv2970c) of Mycobacterium Tuberculosis H37Rv and its Probable Role in Xenobiotic Degradation.Jadeja D, Dogra N, Arya S, Singh G, Singh G, Kaur J2016 Feb26212120
Characterization of a novel exported esterase Rv3036c from Mycobacterium tuberculosis.Chen L, Dang G, Deng X, Cao J, Yu S, Wu D, Pang H, Liu S2014 Dec25224799
Distinct roles of carbohydrate esterase family CE16 acetyl esterases and polymer-acting acetyl xylan esterases in xylan deacetylation.Koutaniemi S, van Gool MP, Juvonen M, Jokela J, Hinz SW, Schols HA, Tenkanen M2013 Dec24140638
Characterization of a novel esterase Rv0045c from Mycobacterium tuberculosis.Guo J, Zheng X, Xu L, Liu Z, Xu K, Li S, Wen T, Liu S, Pang H2010 Oct 120957207
Novel family of carbohydrate esterases, based on identification of the Hypocrea jecorina acetyl esterase gene.Li XL, Skory CD, Cotta MA, Puchart V, Biely P2008 Dec18978092
Fractionation of C-esterase from the hog's kidney extract.Bergmann F, Rimon S1960 Nov16748846
Expression and characterization of the protein Rv1399c from Mycobacterium tuberculosis. A novel carboxyl esterase structurally related to the HSL family.Canaan S, Maurin D, Chahinian H, Pouilly B, Durousseau C, Frassinetti F, Scappuccini-Calvo L, Cambillau C, Bourne Y2004 Oct15373841
Serum esterases. I. Two types of esterase (A and B) hydrolysing p-nitrophenyl acetate, propionate and butyrate, and a method for their determination.ALDRIDGE WN1953 Jan13032041
Biochemical and Structural Characterization of TesA, a Major Thioesterase Required for Outer-Envelope Lipid Biosynthesis in Mycobacterium tuberculosis.Nguyen PC, Nguyen VS, Martin BP, Fourquet P, Camoin L, Spilling CD, Cavalier JF, Cambillau C, Canaan S2018 Dec 730292819
Saccharomyces cerevisiae lipid droplet associated enzyme Ypr147cp shows both TAG lipase and ester hydrolase activities.M NK, V B S C T, B CS, J S B2018 May 2129491250