Enzyme

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EC Tree
     3. Hydrolases
        3.1 Acting on ester bonds
            3.1.1 Carboxylic-ester hydrolases
ID:3.1.1.90
Description:All-trans-retinyl ester 13-cis isomerohydrolase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.1.1.90
BRENDA Enzyme Link: BRENDA 3.1.1.90
KEGG Enzyme Link: KEGG3.1.1.90
BioCyc Enzyme Link: BioCyc 3.1.1.90
ExPASy Enzyme Link: ExPASy3.1.1.90
EC2PDB Enzyme Link: EC2PDB 3.1.1.90
ExplorEnz Enzyme Link: ExplorEnz 3.1.1.90
PRIAM enzyme-specific profiles Link: PRIAM 3.1.1.90
IntEnz Enzyme Link: IntEnz 3.1.1.90
MEDLINE Enzyme Link: MEDLINE 3.1.1.90
MSA:

3.1.1.90;

Phylogenetic Tree:

3.1.1.90;

Uniprot:
M-CSA:
RHEA:31779 an all-trans-retinyl ester + H2O = 13-cis-retinol + a fatty acid + H(+)
RULE(radius=1) [*:1]-[C;H0;+0:2](=[*:3])-[O;H0;+0:4]-[*:5].[OH2;+0:6]>>[*:1]-[C;H0;+0:2](=[*:3])-[OH;+0:6].[*:5]-[OH;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
An alternative isomerohydrolase in the retinal Müller cells of a cone-dominant species.Takahashi Y, Moiseyev G, Chen Y, Nikolaeva O, Ma JX2011 Aug21676174
An enzymatic mechanism for generating the precursor of endogenous 13-cis retinoic acid in the brain.Takahashi Y, Moiseyev G, Chen Y, Farjo K, Nikolaeva O, Ma JX2011 Apr21235714