Enzyme

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EC Tree
     3. Hydrolases
        3.1 Acting on ester bonds
            3.1.1 Carboxylic-ester hydrolases
ID:3.1.1.93
Description:Mycophenolic acid acyl-glucuronide esterase.
Alternative Name: Mycophenolic acid acyl-glucuronide deglucuronidase.
AcMPAG deglucuronidase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.1.1.93
BRENDA Enzyme Link: BRENDA 3.1.1.93
KEGG Enzyme Link: KEGG3.1.1.93
BioCyc Enzyme Link: BioCyc 3.1.1.93
ExPASy Enzyme Link: ExPASy3.1.1.93
EC2PDB Enzyme Link: EC2PDB 3.1.1.93
ExplorEnz Enzyme Link: ExplorEnz 3.1.1.93
PRIAM enzyme-specific profiles Link: PRIAM 3.1.1.93
IntEnz Enzyme Link: IntEnz 3.1.1.93
MEDLINE Enzyme Link: MEDLINE 3.1.1.93
MSA:

3.1.1.93;

Phylogenetic Tree:

3.1.1.93;

Uniprot:
M-CSA:
RHEA:34179 H2O + mycophenolic acid O-acyl-glucuronide = D-glucuronate + H(+) + mycophenolate
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[OH2;+0:6]>>[*:4]-[CH;+0:3](-[*:5])-[OH;+0:6].[*:1]-[OH;+0:2]
Reaction
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References

TitleAuthorsDatePubMed ID
Human α/β hydrolase domain containing 10 (ABHD10) is responsible enzyme for deglucuronidation of mycophenolic acid acyl-glucuronide in liver.Iwamura A, Fukami T, Higuchi R, Nakajima M, Yokoi T2012 Mar 1622294686