EC number:3.1.1.95
| ID: | 3.1.1.95 |
|---|---|
| Description: | Aclacinomycin methylesterase. |
| Alternative Name: |
Aclacinomycin methyl esterase. |
| Cath: | 3.40.50.1820; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.1.1.95 |
| BRENDA Enzyme Link: | BRENDA 3.1.1.95 |
| KEGG Enzyme Link: | KEGG3.1.1.95 |
| BioCyc Enzyme Link: | BioCyc 3.1.1.95 |
| ExPASy Enzyme Link: | ExPASy3.1.1.95 |
| EC2PDB Enzyme Link: | EC2PDB 3.1.1.95 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.1.1.95 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.1.1.95 |
| IntEnz Enzyme Link: | IntEnz 3.1.1.95 |
| MEDLINE Enzyme Link: | MEDLINE 3.1.1.95 |
| RHEA:37891 | aclacinomycin T + H2O = 15-demethylaclacinomycin T + methanol |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH3;+0:3].[OH2;+0:4]>>[*:1]-[OH;+0:2].[CH3;+0:3]-[OH;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Crystal structure of aclacinomycin methylesterase with bound product analogues: implications for anthracycline recognition and mechanism. | Jansson A, Niemi J, Mäntsälä P, Schneider G | 2003 Oct 3 | 12878604 |
| Modifications of aclacinomycin T by aclacinomycin methyl esterase (RdmC) and aclacinomycin-10-hydroxylase (RdmB) from Streptomyces purpurascens. | Wang Y, Niemi J, Airas K, Ylihonko K, Hakala J, Mäntsälä P | 2000 Jul 14 | 11004563 |