EC number:3.1.11.8
Enzyme
Download| EC Tree |
| 3. Hydrolases |
| 3.1 Acting on ester bonds |
| 3.1.11 Exodeoxyribonucleases producing 5'-phosphomonoesters |
| ID: | 3.1.11.8 |
|---|---|
| Description: | Guaosine-5'-diphospho-5'-(DNA) diphosphatase. |
| Alternative Name: |
Pp5'G5'DNA diphosphatase. Pp5'G5'-DNA guanylate hydrolase. Aprataxin. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.1.11.8 |
| BRENDA Enzyme Link: | BRENDA 3.1.11.8 |
| KEGG Enzyme Link: | KEGG3.1.11.8 |
| BioCyc Enzyme Link: | BioCyc 3.1.11.8 |
| ExPASy Enzyme Link: | ExPASy3.1.11.8 |
| EC2PDB Enzyme Link: | EC2PDB 3.1.11.8 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.1.11.8 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.1.11.8 |
| IntEnz Enzyme Link: | IntEnz 3.1.11.8 |
| MEDLINE Enzyme Link: | MEDLINE 3.1.11.8 |
| RHEA:52136 | guanosine-5'-diphospho-5'-(DNA) + H2O = GMP + 2 H(+) + phospho-5'-(DNA) |
| RULE(radius=1) | [*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[O;H0;+0:5]-[*:6].[OH2;+0:7]>>[*:6]-[OH;+0:5].[*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[OH;+0:7] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Characterization of 3'-Phosphate RNA Ligase Paralogs RtcB1, RtcB2, and RtcB3 from Myxococcus xanthus Highlights DNA and RNA 5'-Phosphate Capping Activity of RtcB3. | Maughan WP, Shuman S | 2015 Nov | 26350128 |