Enzyme

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EC Tree
     3. Hydrolases
        3.1 Acting on ester bonds
            3.1.2 Thioester hydrolases
ID:3.1.2.21
Description:Dodecanoyl-[acyl-carrier-protein] hydrolase.
Alternative Name: Lauryl-[acyl-carrier protein] hydrolase.
Dodecyl-[acyl-carrier protein] hydrolase.
Dodecanoyl-acyl-carrier-protein hydrolase.
Cath: 3.10.129.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.1.2.21
BRENDA Enzyme Link: BRENDA 3.1.2.21
KEGG Enzyme Link: KEGG3.1.2.21
BioCyc Enzyme Link: BioCyc 3.1.2.21
ExPASy Enzyme Link: ExPASy3.1.2.21
EC2PDB Enzyme Link: EC2PDB 3.1.2.21
ExplorEnz Enzyme Link: ExplorEnz 3.1.2.21
PRIAM enzyme-specific profiles Link: PRIAM 3.1.2.21
IntEnz Enzyme Link: IntEnz 3.1.2.21
MEDLINE Enzyme Link: MEDLINE 3.1.2.21
MSA:

3.1.2.21;

Phylogenetic Tree:

3.1.2.21;

Uniprot:
M-CSA:
RHEA:30119 dodecanoyl-[ACP] + H2O = dodecanoate + H(+) + holo-[ACP]
RULE(radius=1) [*:1]-[S;H0;+0:2]-[C;H0;+0:3](=[*:4])-[*:5].[OH2;+0:6]>>[*:1]-[SH;+0:2].[*:4]=[C;H0;+0:3](-[*:5])-[OH;+0:6]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The enigmatic acyl carrier protein phosphodiesterase of Escherichia coli: genetic and enzymological characterization.Thomas J, Cronan JE2005 Oct 1416107329
A specific acyl-ACP thioesterase implicated in medium-chain fatty acid production in immature cotyledons of Umbellularia californica.Pollard MR, Anderson L, Fan C, Hawkins DJ, Davies HM1991 Feb 11989513
Developmental induction, purification, and further characterization of 12:0-ACP thioesterase from immature cotyledons of Umbellularia californica.Davies HM, Anderson L, Fan C, Hawkins DJ1991 Oct1898097
A genetic locus required for iron acquisition in Mycobacterium tuberculosis.Krithika R, Marathe U, Saxena P, Ansari MZ, Mohanty D, Gokhale RS2006 Feb 1416461464