EC number:3.1.2.4
| ID: | 3.1.2.4 |
|---|---|
| Description: | 3-hydroxyisobutyryl-CoA hydrolase. |
| Cath: | 3.20.20.80; 3.90.226.10; 3.90.226.40; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.1.2.4 |
| BRENDA Enzyme Link: | BRENDA 3.1.2.4 |
| KEGG Enzyme Link: | KEGG3.1.2.4 |
| BioCyc Enzyme Link: | BioCyc 3.1.2.4 |
| ExPASy Enzyme Link: | ExPASy3.1.2.4 |
| EC2PDB Enzyme Link: | EC2PDB 3.1.2.4 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.1.2.4 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.1.2.4 |
| IntEnz Enzyme Link: | IntEnz 3.1.2.4 |
| MEDLINE Enzyme Link: | MEDLINE 3.1.2.4 |
| RHEA:20888 | 3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+) |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[*:3])-[S;H0;+0:4]-[*:5].[OH2;+0:6]>>[*:5]-[SH;+0:4].[*:1]=[C;H0;+0:2](-[*:3])-[OH;+0:6] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Primary structure and tissue-specific expression of human beta-hydroxyisobutyryl-coenzyme A hydrolase. | Hawes JW, Jaskiewicz J, Shimomura Y, Huang B, Bunting J, Harper ET, Harris RA | 1996 Oct 18 | 8824301 |
| Purification and partial characterization of 3-hydroxyisobutyryl-coenzyme A hydrolase of rat liver. | Shimomura Y, Murakami T, Fujitsuka N, Nakai N, Sato Y, Sugiyama S, Shimomura N, Irwin J, Hawes JW, Harris RA | 1994 May 13 | 8188708 |
| Divergent function in the crotonase superfamily: an anhydride intermediate in the reaction catalyzed by 3-hydroxyisobutyryl-CoA hydrolase. | Wong BJ, Gerlt JA | 2003 Oct 8 | 14518977 |
| The biochemistry of peroxisomal beta-oxidation in the yeast Saccharomyces cerevisiae. | Hiltunen JK, Mursula AM, Rottensteiner H, Wierenga RK, Kastaniotis AJ, Gurvitz A | 2003 Apr | 12697341 |
| chy1, an Arabidopsis mutant with impaired beta-oxidation, is defective in a peroxisomal beta-hydroxyisobutyryl-CoA hydrolase. | Zolman BK, Monroe-Augustus M, Thompson B, Hawes JW, Krukenberg KA, Matsuda SP, Bartel B | 2001 Aug 17 | 11404361 |