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3. Hydrolases

3.1 Acting on ester bonds

3.1.3 Phosphoric-monoester hydrolases

ID:

3.1.3.5

Description:

5'-nucleotidase.

Prosite:

PDOC00627;

PDB:

» show all

Cath:

1.10.150.240; 1.10.150.340; 1.10.3210.10; 3.40.1210.10; 3.60.21.10; 3.90.780.10; 3.90.79.10; 3.40.50.1000; 3.40.50.1240;

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PDB	Click once to unfold,double click to fold. 1HPU; 2USH; 1OID; 1OI8; 1HO5; 4WWL; 1USH; 1OIE; 1HP1; 4H2I; 4H2G; 4H2F; 4H2B; 4H1Y; 4H1S; 3ZU0; 3ZTV; 3GVE;

UniProtKB Enzyme Link:	UniProtKB 3.1.3.5
BRENDA Enzyme Link:	BRENDA 3.1.3.5
KEGG Enzyme Link:	KEGG3.1.3.5
BioCyc Enzyme Link:	BioCyc 3.1.3.5
ExPASy Enzyme Link:	ExPASy3.1.3.5
EC2PDB Enzyme Link:	EC2PDB 3.1.3.5
ExplorEnz Enzyme Link:	ExplorEnz 3.1.3.5
PRIAM enzyme-specific profiles Link:	PRIAM 3.1.3.5
IntEnz Enzyme Link:	IntEnz 3.1.3.5
MEDLINE Enzyme Link:	MEDLINE 3.1.3.5

RHEA:12484	a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate
RULE(radius=1)	[:1]-[P;H0;+0:2](=[:3])(-[:4])-[O;H0;+0:5]-[:6].[OH2;+0:7]>>[:6]-[OH;+0:5].[:1]-[P;H0;+0:2](=[:3])(-[:4])-[OH;+0:7]
Reaction
Core-to-Core	No scaffolds atoms were exchanged as a result of the reaction

Title	Authors	Date	PubMed ID
Crystal structures of the novel cytosolic 5'-nucleotidase IIIB explain its preference for m7GMP.	Monecke T, Buschmann J, Neumann P, Wahle E, Ficner R	2014	24603684
Identification of Drosophila and human 7-methyl GMP-specific nucleotidases.	Buschmann J, Moritz B, Jeske M, Lilie H, Schierhorn A, Wahle E	2013 Jan 25	23223233
The Escherichia coli protein YjjG is a house-cleaning nucleotidase in vivo.	Titz B, Häuser R, Engelbrecher A, Uetz P	2007 May	17286574
Evidence for essential catalytic determinants for human erythrocyte pyrimidine 5'-nucleotidase.	Amici A, Ciccioli K, Naponelli V, Raffaelli N, Magni G	2005 Jul	15968458
General enzymatic screens identify three new nucleotidases in Escherichia coli. Biochemical characterization of SurE, YfbR, and YjjG.	Proudfoot M, Kuznetsova E, Brown G, Rao NN, Kitagawa M, Mori H, Savchenko A, Yakunin AF	2004 Dec 24	15489502
Prostatic acid phosphatase degrades lysophosphatidic acid in seminal plasma.	Tanaka M, Kishi Y, Takanezawa Y, Kakehi Y, Aoki J, Arai H	2004 Jul 30	15280042
Purification and characterization of YfkN, a trifunctional nucleotide phosphoesterase secreted by Bacillus subtilis.	Chambert R, Pereira Y, Petit-Glatron MF	2003 Nov	14688230