EC number:3.1.3.77
Enzyme
Download| EC Tree |
| 3. Hydrolases |
| 3.1 Acting on ester bonds |
| 3.1.3 Phosphoric-monoester hydrolases |
| ID: | 3.1.3.77 |
|---|---|
| Description: | Acireductone synthase. |
| Alternative Name: |
E-1 enolase-phosphatase. |
| Cath: | 1.10.720.60; 3.20.20.110; 3.30.70.150; 3.90.1470.20; 3.40.50.1000; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.1.3.77 |
| BRENDA Enzyme Link: | BRENDA 3.1.3.77 |
| KEGG Enzyme Link: | KEGG3.1.3.77 |
| BioCyc Enzyme Link: | BioCyc 3.1.3.77 |
| ExPASy Enzyme Link: | ExPASy3.1.3.77 |
| EC2PDB Enzyme Link: | EC2PDB 3.1.3.77 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.1.3.77 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.1.3.77 |
| IntEnz Enzyme Link: | IntEnz 3.1.3.77 |
| MEDLINE Enzyme Link: | MEDLINE 3.1.3.77 |
| RHEA:21700 | 5-(methylsulfanyl)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate |
| RULE(radius=1) | [*:1]=[P;H0;+0:2](-[*:3])(-[*:4])-[O;H0;+0:5]-[CH2;+0:6]-[C;H0;+0:7](-[*:8])=[O;H0;+0:9].[OH2;+0:10]>>[*:8]-[C;H0;+0:7](-[OH;+0:9])=[CH;+0:6]-[OH;+0:5].[*:1]=[P;H0;+0:2](-[*:3])(-[*:4])-[OH;+0:10] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The methionine salvage pathway in Klebsiella pneumoniae and rat liver. Identification and characterization of two novel dioxygenases. | Wray JW, Abeles RH | 1995 Feb 17 | 7852397 |
| Purification and characterization of an enzyme involved in oxidative carbon-carbon bond cleavage reactions in the methionine salvage pathway of Klebsiella pneumoniae. | Myers RW, Wray JW, Fish S, Abeles RH | 1993 Nov 25 | 8227039 |
| Crystal structure of human E1 enzyme and its complex with a substrate analog reveals the mechanism of its phosphatase/enolase activity. | Wang H, Pang H, Bartlam M, Rao Z | 2005 May 13 | 15843022 |