Enzyme

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     3. Hydrolases
        3.1 Acting on ester bonds
            3.1.3 Phosphoric-monoester hydrolases
ID:3.1.3.81
Description:Diacylglycerol diphosphate phosphatase.
Alternative Name: Pyrophosphate phosphatase.
DGPP phosphohydrolase.
DGPP phosphatase.
Cath: 1.20.144.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.1.3.81
BRENDA Enzyme Link: BRENDA 3.1.3.81
KEGG Enzyme Link: KEGG3.1.3.81
BioCyc Enzyme Link: BioCyc 3.1.3.81
ExPASy Enzyme Link: ExPASy3.1.3.81
EC2PDB Enzyme Link: EC2PDB 3.1.3.81
ExplorEnz Enzyme Link: ExplorEnz 3.1.3.81
PRIAM enzyme-specific profiles Link: PRIAM 3.1.3.81
IntEnz Enzyme Link: IntEnz 3.1.3.81
MEDLINE Enzyme Link: MEDLINE 3.1.3.81
MSA:

3.1.3.81;

Phylogenetic Tree:

3.1.3.81;

Uniprot:
M-CSA:
RHEA:27449 a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + H(+) + phosphate
RULE(radius=1) [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[OH2;+0:7]>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[OH;+0:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Isolation and characterization of the Saccharomyces cerevisiae LPP1 gene encoding a Mg2+-independent phosphatidate phosphatase.Toke DA, Bennett WL, Oshiro J, Wu WI, Voelker DR, Carman GM1998 Jun 59603941
Mammalian Mg2+-independent phosphatidate phosphatase (PAP2) displays diacylglycerol pyrophosphate phosphatase activity.Dillon DA, Chen X, Zeimetz GM, Wu WI, Waggoner DW, Dewald J, Brindley DN, Carman GM1997 Apr 189099673
The Escherichia coli pgpB gene encodes for a diacylglycerol pyrophosphate phosphatase activity.Dillon DA, Wu WI, Riedel B, Wissing JB, Dowhan W, Carman GM1996 Nov 298940025
Purification and characterization of diacylglycerol pyrophosphate phosphatase from Saccharomyces cerevisiae.Wu WI, Liu Y, Riedel B, Wissing JB, Fischl AS, Carman GM1996 Jan 268567632
Enzymological properties of the LPP1-encoded lipid phosphatase from Saccharomyces cerevisiae.Furneisen JM, Carman GM2000 Feb 2410685032