EC number:3.1.3.95

Enzyme

Download
EC Tree
     3. Hydrolases
        3.1 Acting on ester bonds
            3.1.3 Phosphoric-monoester hydrolases
ID:3.1.3.95
Description:Phosphatidylinositol-3,5-bisphosphate 3-phosphatase.
Alternative Name: PtdIns-3,5-P(2) 3-Ptase.
Cath: 2.30.29.30;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 3.1.3.95
BRENDA Enzyme Link: BRENDA 3.1.3.95
KEGG Enzyme Link: KEGG3.1.3.95
BioCyc Enzyme Link: BioCyc 3.1.3.95
ExPASy Enzyme Link: ExPASy3.1.3.95
EC2PDB Enzyme Link: EC2PDB 3.1.3.95
ExplorEnz Enzyme Link: ExplorEnz 3.1.3.95
PRIAM enzyme-specific profiles Link: PRIAM 3.1.3.95
IntEnz Enzyme Link: IntEnz 3.1.3.95
MEDLINE Enzyme Link: MEDLINE 3.1.3.95

EC number:3.1.3.95

MSA:

3.1.3.95;
Phylogenetic Tree:

3.1.3.95;
Uniprot:
M-CSA:
RHEA:39019 a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate
RULE(radius=1) [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[OH2;+0:7]>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[OH;+0:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The Arabidopsis chromatin modifier ATX1, the myotubularin-like AtMTM and the response to drought.Ding Y, Lapko H, Ndamukong I, Xia Y, Al-Abdallat A, Lalithambika S, Sadder M, Saleh A, Fromm M, Riethoven JJ, Lu G, Avramova Z2009 Nov19901554
Loss of phosphatase activity in myotubularin-related protein 2 is associated with Charcot-Marie-Tooth disease type 4B1.Berger P, Bonneick S, Willi S, Wymann M, Suter U2002 Jun 1512045210
Characterization of MTMR3. an inositol lipid 3-phosphatase with novel substrate specificity.Walker DM, Urbé S, Dove SK, Tenza D, Raposo G, Clague MJ2001 Oct 1611676921