Enzyme

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     3. Hydrolases
        3.1 Acting on ester bonds
            3.1.4 Phosphoric-diester hydrolases
ID:3.1.4.14
Description:[Acyl-carrier-protein] phosphodiesterase.
Alternative Name: ACP phosphodiesterase.
ACP hydrolyase.
[Acyl-carrier-protein] 4'-pantetheine-phosphohydrolase.
Cath: 3.90.470.20;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.1.4.14
BRENDA Enzyme Link: BRENDA 3.1.4.14
KEGG Enzyme Link: KEGG3.1.4.14
BioCyc Enzyme Link: BioCyc 3.1.4.14
ExPASy Enzyme Link: ExPASy3.1.4.14
EC2PDB Enzyme Link: EC2PDB 3.1.4.14
ExplorEnz Enzyme Link: ExplorEnz 3.1.4.14
PRIAM enzyme-specific profiles Link: PRIAM 3.1.4.14
IntEnz Enzyme Link: IntEnz 3.1.4.14
MEDLINE Enzyme Link: MEDLINE 3.1.4.14
MSA:

3.1.4.14;

Phylogenetic Tree:

3.1.4.14;

Uniprot:
M-CSA:
RHEA:20537 H2O + holo-[ACP] = apo-[ACP] + D-pantetheine 4'-phosphate + H(+)
RULE(radius=1) [*:1]=[P;H0;+0:2](-[*:3])(-[*:4])-[O;H0;+0:5]-[*:6].[OH2;+0:7]>>[*:6]-[OH;+0:5].[*:1]=[P;H0;+0:2](-[*:3])(-[*:4])-[OH;+0:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Acyl carrier protein. IX. Acyl carrier protein hydrolase.Vagelos PR, Larrabes AR1967 Apr 254290442
Regulation of fatty acid synthetase activity. The 4'-phosphopantetheine hydrolase of rat liver.Sobhy C1979 Sep 10224058
The enigmatic acyl carrier protein phosphodiesterase of Escherichia coli: genetic and enzymological characterization.Thomas J, Cronan JE2005 Oct 1416107329