Enzyme

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     3. Hydrolases
        3.1 Acting on ester bonds
            3.1.4 Phosphoric-diester hydrolases
ID:3.1.4.43
Description:Glycerophosphoinositol inositolphosphodiesterase.
Alternative Name: Inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase.
D-myo-inositol 1:2-cyclic phosphate 2-phosphohydrolase.
D-myo-inositol 1,2-cyclic phosphate 2-phosphohydrolase.
D-inositol 1,2-cyclic phosphate 2-phosphohydrolase.
1-D-myo-inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase.
1,2-cyclic-inositol-phosphate phosphodiesterase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.1.4.43
BRENDA Enzyme Link: BRENDA 3.1.4.43
KEGG Enzyme Link: KEGG3.1.4.43
BioCyc Enzyme Link: BioCyc 3.1.4.43
ExPASy Enzyme Link: ExPASy3.1.4.43
EC2PDB Enzyme Link: EC2PDB 3.1.4.43
ExplorEnz Enzyme Link: ExplorEnz 3.1.4.43
PRIAM enzyme-specific profiles Link: PRIAM 3.1.4.43
IntEnz Enzyme Link: IntEnz 3.1.4.43
MEDLINE Enzyme Link: MEDLINE 3.1.4.43
MSA:

3.1.4.43;

Phylogenetic Tree:

3.1.4.43;

Uniprot:
M-CSA:
RHEA:14033 H2O + sn-glycero-3-phospho-1D-myo-inositol = 1D-myo-inositol 1-phosphate + glycerol + H(+)
RULE(radius=1) [*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[O;H0;+0:5]-[*:6].[OH2;+0:7]>>[*:6]-[OH;+0:5].[*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[OH;+0:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
The developmentally regulated osteoblast phosphodiesterase GDE3 is glycerophosphoinositol-specific and modulates cell growth.Corda D, Kudo T, Zizza P, Iurisci C, Kawai E, Kato N, Yanaka N, Mariggiò S2009 Sep 1119596859
A phosphodiesterase in rat kidney cortex that hydrolyses glycerylphosphorylinositol.Dawson RM, Hemington N1977 Feb 15192216