Enzyme

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EC Tree
     3. Hydrolases
        3.1 Acting on ester bonds
            3.1.4 Phosphoric-diester hydrolases
ID:3.1.4.45
Description:N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase.
Alternative Name: Lysosomal alpha-N-acetylglucosaminidase.
Alpha-N-acetylglucosaminyl phosphodiesterase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.1.4.45
BRENDA Enzyme Link: BRENDA 3.1.4.45
KEGG Enzyme Link: KEGG3.1.4.45
BioCyc Enzyme Link: BioCyc 3.1.4.45
ExPASy Enzyme Link: ExPASy3.1.4.45
EC2PDB Enzyme Link: EC2PDB 3.1.4.45
ExplorEnz Enzyme Link: ExplorEnz 3.1.4.45
PRIAM enzyme-specific profiles Link: PRIAM 3.1.4.45
IntEnz Enzyme Link: IntEnz 3.1.4.45
MEDLINE Enzyme Link: MEDLINE 3.1.4.45
MSA:

3.1.4.45;

Phylogenetic Tree:

3.1.4.45;

Uniprot:
M-CSA:
RHEA:24372 H2O + N(4)-[6-(N-acetyl-alpha-D-glucosaminyl-1-phospho)-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(glycan)]-L-asparaginyl-[protein] = H(+) + N(4)-[6-phospho-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(glycan)]-L-asparaginyl-[protein] + N-acetyl-D-glucosamine
RULE(radius=1) [*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[O;H0;+0:5]-[*:6].[OH2;+0:7]>>[*:6]-[OH;+0:5].[*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[OH;+0:7]
Reaction
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References

TitleAuthorsDatePubMed ID
Processing of the phosphorylated recognition marker in lysosomal enzymes. Characterization and partial purification of a microsomal alpha-N-acetylglucosaminyl phosphodiesterase.Waheed A, Hasilik A, von Figura K1981 Jun 106263889