| ID: | 3.1.4.46 |
|---|---|
| Description: | Glycerophosphodiester phosphodiesterase. |
| Alternative Name: |
Glycerophosphoryl diester phosphodiesterase. |
| Cath: | 3.20.20.190; |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 3.1.4.46 |
| BRENDA Enzyme Link: | BRENDA 3.1.4.46 |
| KEGG Enzyme Link: | KEGG3.1.4.46 |
| BioCyc Enzyme Link: | BioCyc 3.1.4.46 |
| ExPASy Enzyme Link: | ExPASy3.1.4.46 |
| EC2PDB Enzyme Link: | EC2PDB 3.1.4.46 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.1.4.46 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.1.4.46 |
| IntEnz Enzyme Link: | IntEnz 3.1.4.46 |
| MEDLINE Enzyme Link: | MEDLINE 3.1.4.46 |
| RHEA:29907 | H2O + sn-glycero-3-phospho-(1'-rac-glycerol) = glycerol + H(+) + sn-glycerol 3-phosphate |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[OH2;+0:7]>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[OH;+0:7] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Periplasmic glycerophosphodiester phosphodiesterase of Escherichia coli, a new enzyme of the glp regulon. | Larson TJ, Ehrmann M, Boos W | 1983 May 10 | 6304089 |
| Purification and characterization of glpQ-encoded glycerophosphodiester phosphodiesterase from Escherichia coli K-12. | Larson TJ, van Loo-Bhattacharya AT | 1988 Feb 1 | 2829735 |
| Escherichia coli cytosolic glycerophosphodiester phosphodiesterase (UgpQ) requires Mg2+, Co2+, or Mn2+ for its enzyme activity. | Ohshima N, Yamashita S, Takahashi N, Kuroishi C, Shiro Y, Takio K | 2008 Feb | 18083802 |
| RHEA:29875 | H2O + sn-glycero-3-phospho-L-serine = H(+) + L-serine + sn-glycerol 3-phosphate |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[O;H0;+0:3]-[*:4].[OH2;+0:5]>>[*:1]-[CH2;+0:2]-[OH;+0:5].[*:4]-[OH;+0:3] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Periplasmic glycerophosphodiester phosphodiesterase of Escherichia coli, a new enzyme of the glp regulon. | Larson TJ, Ehrmann M, Boos W | 1983 May 10 | 6304089 |
| Purification and characterization of glpQ-encoded glycerophosphodiester phosphodiesterase from Escherichia coli K-12. | Larson TJ, van Loo-Bhattacharya AT | 1988 Feb 1 | 2829735 |
| Escherichia coli cytosolic glycerophosphodiester phosphodiesterase (UgpQ) requires Mg2+, Co2+, or Mn2+ for its enzyme activity. | Ohshima N, Yamashita S, Takahashi N, Kuroishi C, Shiro Y, Takio K | 2008 Feb | 18083802 |
| RHEA:12969 | a sn-glycero-3-phosphoester + H2O = an alcohol + H(+) + sn-glycerol 3-phosphate |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[*;H0;+0:3].[OH2;+0:4]>>[*;H0;+0:3]-[OH;+0:4].[*:1]-[OH;+0:2] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Periplasmic glycerophosphodiester phosphodiesterase of Escherichia coli, a new enzyme of the glp regulon. | Larson TJ, Ehrmann M, Boos W | 1983 May 10 | 6304089 |
| Purification and characterization of glpQ-encoded glycerophosphodiester phosphodiesterase from Escherichia coli K-12. | Larson TJ, van Loo-Bhattacharya AT | 1988 Feb 1 | 2829735 |
| Characterization of the Arabidopsis glycerophosphodiester phosphodiesterase (GDPD) family reveals a role of the plastid-localized AtGDPD1 in maintaining cellular phosphate homeostasis under phosphate starvation. | Cheng Y, Zhou W, El Sheery NI, Peters C, Li M, Wang X, Huang J | 2011 Jun | 21323773 |
| Escherichia coli cytosolic glycerophosphodiester phosphodiesterase (UgpQ) requires Mg2+, Co2+, or Mn2+ for its enzyme activity. | Ohshima N, Yamashita S, Takahashi N, Kuroishi C, Shiro Y, Takio K | 2008 Feb | 18083802 |