Enzyme

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     3. Hydrolases
        3.1 Acting on ester bonds
            3.1.4 Phosphoric-diester hydrolases
ID:3.1.4.46
Description:Glycerophosphodiester phosphodiesterase.
Alternative Name: Glycerophosphoryl diester phosphodiesterase.
Cath: 3.20.20.190;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.1.4.46
BRENDA Enzyme Link: BRENDA 3.1.4.46
KEGG Enzyme Link: KEGG3.1.4.46
BioCyc Enzyme Link: BioCyc 3.1.4.46
ExPASy Enzyme Link: ExPASy3.1.4.46
EC2PDB Enzyme Link: EC2PDB 3.1.4.46
ExplorEnz Enzyme Link: ExplorEnz 3.1.4.46
PRIAM enzyme-specific profiles Link: PRIAM 3.1.4.46
IntEnz Enzyme Link: IntEnz 3.1.4.46
MEDLINE Enzyme Link: MEDLINE 3.1.4.46
MSA:

3.1.4.46;

Phylogenetic Tree:

3.1.4.46;

Uniprot:
M-CSA:
RHEA:29907 H2O + sn-glycero-3-phospho-(1'-rac-glycerol) = glycerol + H(+) + sn-glycerol 3-phosphate
RULE(radius=1) [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[OH2;+0:7]>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[OH;+0:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Periplasmic glycerophosphodiester phosphodiesterase of Escherichia coli, a new enzyme of the glp regulon.Larson TJ, Ehrmann M, Boos W1983 May 106304089
Purification and characterization of glpQ-encoded glycerophosphodiester phosphodiesterase from Escherichia coli K-12.Larson TJ, van Loo-Bhattacharya AT1988 Feb 12829735
Escherichia coli cytosolic glycerophosphodiester phosphodiesterase (UgpQ) requires Mg2+, Co2+, or Mn2+ for its enzyme activity.Ohshima N, Yamashita S, Takahashi N, Kuroishi C, Shiro Y, Takio K2008 Feb18083802

RHEA:29875 H2O + sn-glycero-3-phospho-L-serine = H(+) + L-serine + sn-glycerol 3-phosphate
RULE(radius=1) [*:1]-[CH2;+0:2]-[O;H0;+0:3]-[*:4].[OH2;+0:5]>>[*:1]-[CH2;+0:2]-[OH;+0:5].[*:4]-[OH;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Periplasmic glycerophosphodiester phosphodiesterase of Escherichia coli, a new enzyme of the glp regulon.Larson TJ, Ehrmann M, Boos W1983 May 106304089
Purification and characterization of glpQ-encoded glycerophosphodiester phosphodiesterase from Escherichia coli K-12.Larson TJ, van Loo-Bhattacharya AT1988 Feb 12829735
Escherichia coli cytosolic glycerophosphodiester phosphodiesterase (UgpQ) requires Mg2+, Co2+, or Mn2+ for its enzyme activity.Ohshima N, Yamashita S, Takahashi N, Kuroishi C, Shiro Y, Takio K2008 Feb18083802

RHEA:12969 a sn-glycero-3-phosphoester + H2O = an alcohol + H(+) + sn-glycerol 3-phosphate
RULE(radius=1) [*:1]-[O;H0;+0:2]-[*;H0;+0:3].[OH2;+0:4]>>[*;H0;+0:3]-[OH;+0:4].[*:1]-[OH;+0:2]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Periplasmic glycerophosphodiester phosphodiesterase of Escherichia coli, a new enzyme of the glp regulon.Larson TJ, Ehrmann M, Boos W1983 May 106304089
Purification and characterization of glpQ-encoded glycerophosphodiester phosphodiesterase from Escherichia coli K-12.Larson TJ, van Loo-Bhattacharya AT1988 Feb 12829735
Characterization of the Arabidopsis glycerophosphodiester phosphodiesterase (GDPD) family reveals a role of the plastid-localized AtGDPD1 in maintaining cellular phosphate homeostasis under phosphate starvation.Cheng Y, Zhou W, El Sheery NI, Peters C, Li M, Wang X, Huang J2011 Jun21323773
Escherichia coli cytosolic glycerophosphodiester phosphodiesterase (UgpQ) requires Mg2+, Co2+, or Mn2+ for its enzyme activity.Ohshima N, Yamashita S, Takahashi N, Kuroishi C, Shiro Y, Takio K2008 Feb18083802