EC number:3.1.4.57

Enzyme

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EC Tree
     3. Hydrolases
        3.1 Acting on ester bonds
            3.1.4 Phosphoric-diester hydrolases
ID:3.1.4.57
Description:Phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase.
Alternative Name: Cyclic phosphate dihydrolase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 3.1.4.57
BRENDA Enzyme Link: BRENDA 3.1.4.57
KEGG Enzyme Link: KEGG3.1.4.57
BioCyc Enzyme Link: BioCyc 3.1.4.57
ExPASy Enzyme Link: ExPASy3.1.4.57
EC2PDB Enzyme Link: EC2PDB 3.1.4.57
ExplorEnz Enzyme Link: ExplorEnz 3.1.4.57
PRIAM enzyme-specific profiles Link: PRIAM 3.1.4.57
IntEnz Enzyme Link: IntEnz 3.1.4.57
MEDLINE Enzyme Link: MEDLINE 3.1.4.57

EC number:3.1.4.57

MSA:

3.1.4.57;
Phylogenetic Tree:

3.1.4.57;
Uniprot:
M-CSA:
RHEA:41616 D-ribose 2,5-bisphosphate + H2O = D-ribose 5-phosphate + phosphate
RULE(radius=1) [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[OH2;+0:7]>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[OH;+0:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Discovery of a cyclic phosphodiesterase that catalyzes the sequential hydrolysis of both ester bonds to phosphorus.Ghodge SV, Cummings JA, Williams HJ, Raushel FM2013 Nov 624147537
RHEA:41612 alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + H2O = D-ribose 2,5-bisphosphate + H(+)
RULE(radius=1) [*:1]=[P;H0;+0:2](-[*:3])(-[*:4])-[O;H0;+0:5]-[*:6].[OH2;+0:7]>>([*:6]-[OH;+0:5].[*:1]=[P;H0;+0:2](-[*:3])(-[*:4])-[OH;+0:7])
Reaction
Core-to-Core More

References

TitleAuthorsDatePubMed ID
Discovery of a cyclic phosphodiesterase that catalyzes the sequential hydrolysis of both ester bonds to phosphorus.Ghodge SV, Cummings JA, Williams HJ, Raushel FM2013 Nov 624147537