EC number:3.1.6.8
| ID: | 3.1.6.8 | ||
|---|---|---|---|
| Description: | Cerebroside-sulfatase. | ||
| Alternative Name: |
Arylsulfatase A. | ||
| Prosite: | PDOC00117; | ||
| PDB: |
|
||
| Cath: | 3.30.1120.10; 3.40.720.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.1.6.8 |
| BRENDA Enzyme Link: | BRENDA 3.1.6.8 |
| KEGG Enzyme Link: | KEGG3.1.6.8 |
| BioCyc Enzyme Link: | BioCyc 3.1.6.8 |
| ExPASy Enzyme Link: | ExPASy3.1.6.8 |
| EC2PDB Enzyme Link: | EC2PDB 3.1.6.8 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.1.6.8 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.1.6.8 |
| IntEnz Enzyme Link: | IntEnz 3.1.6.8 |
| MEDLINE Enzyme Link: | MEDLINE 3.1.6.8 |
| RHEA:21300 | H2O + N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine = an N-acyl-beta-D-galactosyl-sphing-4-enine + H(+) + sulfate |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[S;H0;+0:3](=[*:4])(=[*:5])-[*:6].[OH2;+0:7]>>[*:1]-[OH;+0:2].[*:4]=[S;H0;+0:3](=[*:5])(-[*:6])-[OH;+0:7] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A new analytical bench assay for the determination of arylsulfatase a activity toward galactosyl-3-sulfate ceramide: implication for metachromatic leukodystrophy diagnosis. | Morena F, di Girolamo I, Emiliani C, Gritti A, Biffi A, Martino S | 2014 Jan 7 | 24294900 |
| Crystal structure of a covalent intermediate of endogenous human arylsulfatase A. | Chruszcz M, Laidler P, Monkiewicz M, Ortlund E, Lebioda L, Lewinski K | 2003 Aug 1 | 12888274 |