EC number:3.1.8.1

Enzyme

Download
EC Tree
     3. Hydrolases
        3.1 Acting on ester bonds
            3.1.8 Phosphoric-triester hydrolases
ID:3.1.8.1
Description:Aryldialkylphosphatase.
Alternative Name: Phosphotriesterase.
Paraoxonase.
Paraoxon hydrolase.
Aryltriphosphatase.
A-esterase.
Prosite: PDOC01026;
PDB:
PDBScop
4LEF 8031065; 8043443; 8031065; 8043443; 8031065; 8043443; 8031065; 8043443; 8031065; 8043443; 8031065; 8043443; 8031065; 8043443; 8031065; 8043443;
1BF6 8031065; 8043443; 8031065; 8043443;
1P6C 8025892; 8038271; 8025892; 8038271;
1P6B 8025892; 8038271; 8025892; 8038271;
6FU0 8021115; 8033495; 8021115; 8033495; 8021115; 8033495; 8021115; 8033495;
 » show all
Cath: 3.20.20.140; 3.60.15.10; 3.90.230.10; 2.120.10.30; 3.40.350.10;

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 3.1.8.1
BRENDA Enzyme Link: BRENDA 3.1.8.1
KEGG Enzyme Link: KEGG3.1.8.1
BioCyc Enzyme Link: BioCyc 3.1.8.1
ExPASy Enzyme Link: ExPASy3.1.8.1
EC2PDB Enzyme Link: EC2PDB 3.1.8.1
ExplorEnz Enzyme Link: ExplorEnz 3.1.8.1
PRIAM enzyme-specific profiles Link: PRIAM 3.1.8.1
IntEnz Enzyme Link: IntEnz 3.1.8.1
MEDLINE Enzyme Link: MEDLINE 3.1.8.1

EC number:3.1.8.1

MSA:

3.1.8.1;
Phylogenetic Tree:

3.1.8.1;
Uniprot:
M-CSA:
RHEA:18053 H2O + paraoxon = 4-nitrophenol + diethylphosphate + 2 H(+)
RULE(radius=1) [*:1]=[P;H0;+0:2](-[*:3])(-[*:4])-[O;H0;+0:5]-[*:6].[OH2;+0:7]>>[*:6]-[OH;+0:5].[*:1]=[P;H0;+0:2](-[*:3])(-[*:4])-[OH;+0:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
A novel thermostable arylesterase from the archaeon Sulfolobus solfataricus P1: purification, characterization, and expression.Park YJ, Yoon SJ, Lee HB2008 Dec18931117
A thermostable phosphotriesterase from the archaeon Sulfolobus solfataricus: cloning, overexpression and properties.Merone L, Mandrich L, Rossi M, Manco G2005 Aug15909078