EC number:3.11.1.2
Enzyme
Download| EC Tree |
| 3. Hydrolases |
| 3.11 Acting on carbon-phosphorus bonds |
| 3.11.1 Acting on carbon-phosphorus bonds (only sub-subclass identified to date) |
| ID: | 3.11.1.2 |
|---|---|
| Description: | Phosphonoacetate hydrolase. |
| Cath: | 3.30.1360.110; 3.40.720.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.11.1.2 |
| BRENDA Enzyme Link: | BRENDA 3.11.1.2 |
| KEGG Enzyme Link: | KEGG3.11.1.2 |
| BioCyc Enzyme Link: | BioCyc 3.11.1.2 |
| ExPASy Enzyme Link: | ExPASy3.11.1.2 |
| EC2PDB Enzyme Link: | EC2PDB 3.11.1.2 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.11.1.2 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.11.1.2 |
| IntEnz Enzyme Link: | IntEnz 3.11.1.2 |
| MEDLINE Enzyme Link: | MEDLINE 3.11.1.2 |
| RHEA:16749 | H2O + phosphonoacetate = acetate + H(+) + phosphate |
| RULE(radius=1) | [*:1]-[CH2;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[OH2;+0:7]>>[*:1]-[CH3;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[OH;+0:7] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Cloning of the phosphonoacetate hydrolase gene from Pseudomonas fluorescens 23F encoding a new type of carbon-phosphorus bond cleaving enzyme and its expression in Escherichia coli and Pseudomonas putida. | Kulakova AN, Kulakov LA, Quinn JP | 1997 Aug 11 | 9300819 |
| The purification and properties of phosphonoacetate hydrolase, a novel carbon-phosphorus bond-cleavage enzyme from Pseudomonas fluorescens 23F. | McGrath JW, Wisdom GB, McMullan G, Larkin MJ, Quinn JP | 1995 Nov 15 | 8529644 |
| In vitro characterization of a phosphate starvation-independent carbon-phosphorus bond cleavage activity in Pseudomonas fluorescens 23F. | McMullan G, Quinn JP | 1994 Jan | 8288524 |
| Phosphonoacetate hydrolase from Penicillium oxalicum: purification and properties, phosphate starvation-independent expression, and partial sequencing. | Klimek-Ochab M, Raucci G, Lejczak B, Forlani G | 2006 Mar | 16129582 |
| A metal-independent hydrolase from a Penicillium oxalicum strain able to use phosphonoacetic acid as the only phosphorus source. | Klimek-Ochab M, Lejczak B, Forlani G | 2003 May 28 | 12770709 |