EC number:3.11.1.3
Enzyme
Download| EC Tree |
| 3. Hydrolases |
| 3.11 Acting on carbon-phosphorus bonds |
| 3.11.1 Acting on carbon-phosphorus bonds (only sub-subclass identified to date) |
| ID: | 3.11.1.3 |
|---|---|
| Description: | Phosphonopyruvate hydrolase. |
| Alternative Name: |
PPH. |
| Cath: | 3.20.20.60; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.11.1.3 |
| BRENDA Enzyme Link: | BRENDA 3.11.1.3 |
| KEGG Enzyme Link: | KEGG3.11.1.3 |
| BioCyc Enzyme Link: | BioCyc 3.11.1.3 |
| ExPASy Enzyme Link: | ExPASy3.11.1.3 |
| EC2PDB Enzyme Link: | EC2PDB 3.11.1.3 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.11.1.3 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.11.1.3 |
| IntEnz Enzyme Link: | IntEnz 3.11.1.3 |
| MEDLINE Enzyme Link: | MEDLINE 3.11.1.3 |
| RHEA:16673 | 3-phosphonopyruvate + H2O = H(+) + phosphate + pyruvate |
| RULE(radius=1) | [*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[CH2;+0:5]-[*:6].[OH2;+0:7]>>[*:6]-[CH3;+0:5].[*:1]-[P;H0;+0:2](=[*:3])(-[*:4])-[OH;+0:7] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Structure and kinetics of phosphonopyruvate hydrolase from Variovorax sp. Pal2: new insight into the divergence of catalysis within the PEP mutase/isocitrate lyase superfamily. | Chen CC, Han Y, Niu W, Kulakova AN, Howard A, Quinn JP, Dunaway-Mariano D, Herzberg O | 2006 Sep 26 | 16981709 |
| The purification and characterization of phosphonopyruvate hydrolase, a novel carbon-phosphorus bond cleavage enzyme from Variovorax sp Pal2. | Kulakova AN, Wisdom GB, Kulakov LA, Quinn JP | 2003 Jun 27 | 12697754 |
| Initial in vitro characterisation of phosphonopyruvate hydrolase, a novel phosphate starvation-independent, carbon-phosphorus bond cleavage enzyme in Burkholderia cepacia Pal6. | Ternan NG, Hamilton JT, Quinn JP | 2000 Jan | 10648102 |