EC number:3.2.1.106

Enzyme

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     3. Hydrolases
        3.2 Glycosylases
            3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
ID:3.2.1.106
Description:Mannosyl-oligosaccharide glucosidase.
Alternative Name: Processing A-glucosidase I.
Glc3Man9NAc(2) oligosaccharide glucosidase.
Cath: 1.50.10.10; 2.70.98.110;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 3.2.1.106
BRENDA Enzyme Link: BRENDA 3.2.1.106
KEGG Enzyme Link: KEGG3.2.1.106
BioCyc Enzyme Link: BioCyc 3.2.1.106
ExPASy Enzyme Link: ExPASy3.2.1.106
EC2PDB Enzyme Link: EC2PDB 3.2.1.106
ExplorEnz Enzyme Link: ExplorEnz 3.2.1.106
PRIAM enzyme-specific profiles Link: PRIAM 3.2.1.106
IntEnz Enzyme Link: IntEnz 3.2.1.106
MEDLINE Enzyme Link: MEDLINE 3.2.1.106

EC number:3.2.1.106

MSA:

3.2.1.106;
Phylogenetic Tree:

3.2.1.106;
Uniprot:
M-CSA:
RHEA:55988 H2O + N(4)-(alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc)-L-asparaginyl-[protein] = beta-D-glucose + N(4)-(alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc)-L-asparaginyl-[protein]
RULE(radius=1)
Reaction
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References

TitleAuthorsDatePubMed ID
Characterization of a glucosidase involved in an initial step in the processing of oligosaccharide chains.Elting JJ, Chen WW, Lennarz WJ1980 Mar 257358674
Substrate specificities of rat liver microsomal glucosidases which process glycoproteins.Grinna LS, Robbins PW1980 Mar 257358666
Partial purification and characterization of the glucosidases involved in the processing of asparagine-linked oligosaccharides.Michael JM, Kornfeld S1980 Jan7356331
Partial purification from Saccharomyces cerevisiae of a soluble glucosidase which removes the terminal glucose from the oligosaccharide Glc3Man9GlcNAc2.Kilker RD Jr, Saunier B, Tkacz JS, Herscovics A1981 May 257014569
Glycoprotein biosynthesis. Rat liver microsomal glucosidases which process oligosaccharides.Grinna LS, Robbins PW1979 Sep 25479161