Enzyme

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     3. Hydrolases
        3.2 Glycosylases
            3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
ID:3.2.1.107
Description:Protein-glucosylgalactosylhydroxylysine glucosidase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.2.1.107
BRENDA Enzyme Link: BRENDA 3.2.1.107
KEGG Enzyme Link: KEGG3.2.1.107
BioCyc Enzyme Link: BioCyc 3.2.1.107
ExPASy Enzyme Link: ExPASy3.2.1.107
EC2PDB Enzyme Link: EC2PDB 3.2.1.107
ExplorEnz Enzyme Link: ExplorEnz 3.2.1.107
PRIAM enzyme-specific profiles Link: PRIAM 3.2.1.107
IntEnz Enzyme Link: IntEnz 3.2.1.107
MEDLINE Enzyme Link: MEDLINE 3.2.1.107
MSA:

3.2.1.107;

Phylogenetic Tree:

3.2.1.107;

Uniprot:
M-CSA:
RHEA:11068 (5R)-5-O-[alpha-D-glucosyl-(1->2)-beta-D-galactosyl]-5-hydroxy-L-lysyl-[procollagen] + H2O = (5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysyl-[procollagen] + D-glucose
RULE(radius=1) [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[OH2;+0:6]>>[*:4]-[CH;+0:3](-[*:5])-[OH;+0:6].[*:1]-[OH;+0:2]
Reaction
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References

TitleAuthorsDatePubMed ID
Enzymatic hydrolysis of disaccharide unit of collagen. Isolation of 2-O-alpha-D-glucopyranosyl-O-beta-D-galactopyranosyl-hydroxylysine glucohydrolase from rat spleens.Hamazaki H, Hotta K1980 Oct7460918
Purification and characterization of an alpha-glucosidase specific for hydroxylysine-linked disaccharide of collagen.Hamazaki H, Hotta K1979 Oct 10385589
Catalytic site of human protein-glucosylgalactosylhydroxylysine glucosidase: Three crucial carboxyl residues were determined by cloning and site-directed mutagenesis.Hamazaki H, Hamazaki MH2016 Jan 1526682924
Studies on the catabolism of the hydroxylysine-linked disaccharide units of basement membranes and collagens. Isolation and characterization of a rat kidney alpha-glucosidase of high specificity.Sternberg M, Spiro RG1979 Oct 25385599