EC Tree |
3. Hydrolases |
3.2 Glycosylases |
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds |
ID: | 3.2.1.107 |
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Description: | Protein-glucosylgalactosylhydroxylysine glucosidase. |
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Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.UniProtKB Enzyme Link: | UniProtKB 3.2.1.107 |
BRENDA Enzyme Link: | BRENDA 3.2.1.107 |
KEGG Enzyme Link: | KEGG3.2.1.107 |
BioCyc Enzyme Link: | BioCyc 3.2.1.107 |
ExPASy Enzyme Link: | ExPASy3.2.1.107 |
EC2PDB Enzyme Link: | EC2PDB 3.2.1.107 |
ExplorEnz Enzyme Link: | ExplorEnz 3.2.1.107 |
PRIAM enzyme-specific profiles Link: | PRIAM 3.2.1.107 |
IntEnz Enzyme Link: | IntEnz 3.2.1.107 |
MEDLINE Enzyme Link: | MEDLINE 3.2.1.107 |
MSA: | |
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Phylogenetic Tree: | |
Uniprot: | |
M-CSA: |
RHEA:11068 | (5R)-5-O-[alpha-D-glucosyl-(1->2)-beta-D-galactosyl]-5-hydroxy-L-lysyl-[procollagen] + H2O = (5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysyl-[procollagen] + D-glucose |
RULE(radius=1) | [*:1]-[O;H0;+0:2]-[CH;+0:3](-[*:4])-[*:5].[OH2;+0:6]>>[*:4]-[CH;+0:3](-[*:5])-[OH;+0:6].[*:1]-[OH;+0:2] |
Reaction | ![]() |
Core-to-Core |
Title | Authors | Date | PubMed ID |
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Enzymatic hydrolysis of disaccharide unit of collagen. Isolation of 2-O-alpha-D-glucopyranosyl-O-beta-D-galactopyranosyl-hydroxylysine glucohydrolase from rat spleens. | Hamazaki H, Hotta K | 1980 Oct | 7460918 |
Purification and characterization of an alpha-glucosidase specific for hydroxylysine-linked disaccharide of collagen. | Hamazaki H, Hotta K | 1979 Oct 10 | 385589 |
Catalytic site of human protein-glucosylgalactosylhydroxylysine glucosidase: Three crucial carboxyl residues were determined by cloning and site-directed mutagenesis. | Hamazaki H, Hamazaki MH | 2016 Jan 15 | 26682924 |
Studies on the catabolism of the hydroxylysine-linked disaccharide units of basement membranes and collagens. Isolation and characterization of a rat kidney alpha-glucosidase of high specificity. | Sternberg M, Spiro RG | 1979 Oct 25 | 385599 |