EC Tree |
3. Hydrolases |
3.2 Glycosylases |
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds |
ID: | 3.2.1.108 | ||
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Description: | Lactase. | ||
Prosite: | PDOC00495; | ||
PDB: |
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Cath: | 3.20.20.80; 3.40.50.880; 2.102.20.10; 2.60.120.260; 2.60.220.20; 2.60.390.10; 2.60.40.10; 2.60.40.1180; 2.70.98.10; |
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Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.UniProtKB Enzyme Link: | UniProtKB 3.2.1.108 |
BRENDA Enzyme Link: | BRENDA 3.2.1.108 |
KEGG Enzyme Link: | KEGG3.2.1.108 |
BioCyc Enzyme Link: | BioCyc 3.2.1.108 |
ExPASy Enzyme Link: | ExPASy3.2.1.108 |
EC2PDB Enzyme Link: | EC2PDB 3.2.1.108 |
ExplorEnz Enzyme Link: | ExplorEnz 3.2.1.108 |
PRIAM enzyme-specific profiles Link: | PRIAM 3.2.1.108 |
IntEnz Enzyme Link: | IntEnz 3.2.1.108 |
MEDLINE Enzyme Link: | MEDLINE 3.2.1.108 |
MSA: | |
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Phylogenetic Tree: | |
Uniprot: | |
M-CSA: |
RHEA:10076 | H2O + lactose = D-galactose + D-glucose |
RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:4]-[*:5].[OH2;+0:6]>>[*:1]-[CH;+0:2](-[*:3])-[OH;+0:6].[*:5]-[OH;+0:4] |
Reaction | ![]() |
Core-to-Core |
Title | Authors | Date | PubMed ID |
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Further characterization of intestinal lactase/phlorizin hydrolase. | Skovbjerg H, Norén O, Sjöström H, Danielsen EM, Enevoldsen BS | 1982 Sep 22 | 6814489 |
Dietary flavonoid and isoflavone glycosides are hydrolysed by the lactase site of lactase phlorizin hydrolase. | Day AJ, Cañada FJ, Díaz JC, Kroon PA, Mclauchlan R, Faulds CB, Plumb GW, Morgan MR, Williamson G | 2000 Feb 25 | 10692580 |