EC number:3.2.1.123

Enzyme

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     3. Hydrolases
        3.2 Glycosylases
            3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
ID:3.2.1.123
Description:Endoglycosylceramidase.
Alternative Name: Oligoglycosylglucosylceramide glycohydrolase.
Endoglycoceramidase.
Endo-glucosylceramidase.
Cath: 3.20.20.80; 2.60.40.1180;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 3.2.1.123
BRENDA Enzyme Link: BRENDA 3.2.1.123
KEGG Enzyme Link: KEGG3.2.1.123
BioCyc Enzyme Link: BioCyc 3.2.1.123
ExPASy Enzyme Link: ExPASy3.2.1.123
EC2PDB Enzyme Link: EC2PDB 3.2.1.123
ExplorEnz Enzyme Link: ExplorEnz 3.2.1.123
PRIAM enzyme-specific profiles Link: PRIAM 3.2.1.123
IntEnz Enzyme Link: IntEnz 3.2.1.123
MEDLINE Enzyme Link: MEDLINE 3.2.1.123

EC number:3.2.1.123

MSA:

3.2.1.123;
Phylogenetic Tree:

3.2.1.123;
Uniprot:
M-CSA:
RHEA:22288 an oligoglycosyl-(1->4)-glucosyl-(1<->1)-ceramide + H2O = an oligoglycosyl-(1->4)-beta-D-glucose + N-acyl-sphingoid base
RULE(radius=1) [*:1]-[CH2;+0:2]-[O;H0;+0:3]-[*:4].[OH2;+0:5]>>[*:1]-[CH2;+0:2]-[OH;+0:5].[*:4]-[OH;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
A novel glycosphingolipid-degrading enzyme cleaves the linkage between the oligosaccharide and ceramide of neutral and acidic glycosphingolipids.Ito M, Yamagata T1986 Oct 253771534
Unique catabolic pathway of glycosphingolipids in a hydrozoan, Hydra magnipapillata, involving endoglycoceramidase.Horibata Y, Sakaguchi K, Okino N, Iida H, Inagaki M, Fujisawa T, Hama Y, Ito M2004 Aug 615320336
Purification, characterization, and cDNA cloning of a novel acidic endoglycoceramidase from the jellyfish, Cyanea nozakii.Horibata Y, Okino N, Ichinose S, Omori A, Ito M2000 Oct 610882727