EC number:3.2.1.179
Enzyme
Download| EC Tree |
| 3. Hydrolases |
| 3.2 Glycosylases |
| 3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds |
| ID: | 3.2.1.179 |
|---|---|
| Description: | Gellan tetrasaccharide unsaturated glucuronosyl hydrolase. |
| Alternative Name: |
Unsaturated glucuronyl hydrolase. Gellan tetrasaccharide unsaturated glucuronyl hydrolase. |
| Cath: | 1.50.10.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.2.1.179 |
| BRENDA Enzyme Link: | BRENDA 3.2.1.179 |
| KEGG Enzyme Link: | KEGG3.2.1.179 |
| BioCyc Enzyme Link: | BioCyc 3.2.1.179 |
| ExPASy Enzyme Link: | ExPASy3.2.1.179 |
| EC2PDB Enzyme Link: | EC2PDB 3.2.1.179 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.2.1.179 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.2.1.179 |
| IntEnz Enzyme Link: | IntEnz 3.2.1.179 |
| MEDLINE Enzyme Link: | MEDLINE 3.2.1.179 |
EC number:3.2.1.179
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:31635 | beta-D-Delta(4)-GlcpA-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-D-Glcp + H2O = 5-dehydro-4-deoxy-D-glucuronate + beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-D-Glcp |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1=[CH;+0:3]-[*:4]-[*:5]-[CH;+0:6](-[O;H0;+0:7]-[*:8])-[O;H0;+0:9]-1.[OH2;+0:10]>>[*:1]-[C;H0;+0:2](=[O;H0;+0:9])-[CH2;+0:3]-[*:4]-[*:5]-[CH;+0:6]=[O;H0;+0:10].[*:8]-[OH;+0:7] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Structural determinants in streptococcal unsaturated glucuronyl hydrolase for recognition of glycosaminoglycan sulfate groups. | Nakamichi Y, Maruyama Y, Mikami B, Hashimoto W, Murata K | 2011 Feb 25 | 21147778 |
| Substrate recognition by unsaturated glucuronyl hydrolase from Bacillus sp. GL1. | Itoh T, Hashimoto W, Mikami B, Murata K | 2006 May 26 | 16630576 |
| Crystal structure of unsaturated glucuronyl hydrolase, responsible for the degradation of glycosaminoglycan, from Bacillus sp. GL1 at 1.8 A resolution. | Itoh T, Akao S, Hashimoto W, Mikami B, Murata K | 2004 Jul 23 | 15148314 |
| Unsaturated glucuronyl hydrolase of Bacillus sp. GL1: novel enzyme prerequisite for metabolism of unsaturated oligosaccharides produced by polysaccharide lyases. | Hashimoto W, Kobayashi E, Nankai H, Sato N, Miya T, Kawai S, Murata K | 1999 Aug 15 | 10441389 |
| RHEA:31651 | beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1=[CH;+0:3]-[*:4]-[*:5]-[CH;+0:6](-[O;H0;+0:7]-[*:8])-[O;H0;+0:9]-1.[OH2;+0:10]>>[*:1]-[C;H0;+0:2](=[O;H0;+0:9])-[CH2;+0:3]-[*:4]-[*:5]-[CH;+0:6]=[O;H0;+0:10].[*:8]-[OH;+0:7] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Substrate recognition by unsaturated glucuronyl hydrolase from Bacillus sp. GL1. | Itoh T, Hashimoto W, Mikami B, Murata K | 2006 May 26 | 16630576 |
| Crystal structure of unsaturated glucuronyl hydrolase, responsible for the degradation of glycosaminoglycan, from Bacillus sp. GL1 at 1.8 A resolution. | Itoh T, Akao S, Hashimoto W, Mikami B, Murata K | 2004 Jul 23 | 15148314 |
| Unsaturated glucuronyl hydrolase of Bacillus sp. GL1: novel enzyme prerequisite for metabolism of unsaturated oligosaccharides produced by polysaccharide lyases. | Hashimoto W, Kobayashi E, Nankai H, Sato N, Miya T, Kawai S, Murata K | 1999 Aug 15 | 10441389 |
| RHEA:31655 | 4-deoxy-Delta(4)-beta-D-GlcpA2S-(1->3)-beta-D-GalpNAc + H2O = 5-dehydro-4-deoxy-2-O-sulfo-D-glucuronate + N-acetyl-beta-D-galactosamine |
| RULE(radius=1) | [*:1]-[CH;+0:2](-[*:3])-[O;H0;+0:4]-[CH;+0:5]1-[*:6]-[*:7]-[CH;+0:8]=[C;H0;+0:9](-[*:10])-[O;H0;+0:11]-1.[OH2;+0:12]>>[*:10]-[C;H0;+0:9](=[O;H0;+0:11])-[CH2;+0:8]-[*:7]-[*:6]-[CH;+0:5]=[O;H0;+0:4].[*:1]-[CH;+0:2](-[*:3])-[OH;+0:12] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Substrate recognition by unsaturated glucuronyl hydrolase from Bacillus sp. GL1. | Itoh T, Hashimoto W, Mikami B, Murata K | 2006 May 26 | 16630576 |
| Crystal structure of unsaturated glucuronyl hydrolase, responsible for the degradation of glycosaminoglycan, from Bacillus sp. GL1 at 1.8 A resolution. | Itoh T, Akao S, Hashimoto W, Mikami B, Murata K | 2004 Jul 23 | 15148314 |
| Unsaturated glucuronyl hydrolase of Bacillus sp. GL1: novel enzyme prerequisite for metabolism of unsaturated oligosaccharides produced by polysaccharide lyases. | Hashimoto W, Kobayashi E, Nankai H, Sato N, Miya T, Kawai S, Murata K | 1999 Aug 15 | 10441389 |
| RHEA:31659 | beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GlcpNAc + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine |
| RULE(radius=1) | [*:1]-[C;H0;+0:2]1=[CH;+0:3]-[*:4]-[*:5]-[CH;+0:6](-[O;H0;+0:7]-[*:8])-[O;H0;+0:9]-1.[OH2;+0:10]>>[*:1]-[C;H0;+0:2](=[O;H0;+0:9])-[CH2;+0:3]-[*:4]-[*:5]-[CH;+0:6]=[O;H0;+0:10].[*:8]-[OH;+0:7] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Substrate recognition by unsaturated glucuronyl hydrolase from Bacillus sp. GL1. | Itoh T, Hashimoto W, Mikami B, Murata K | 2006 May 26 | 16630576 |
| Crystal structure of unsaturated glucuronyl hydrolase, responsible for the degradation of glycosaminoglycan, from Bacillus sp. GL1 at 1.8 A resolution. | Itoh T, Akao S, Hashimoto W, Mikami B, Murata K | 2004 Jul 23 | 15148314 |
| Unsaturated glucuronyl hydrolase of Bacillus sp. GL1: novel enzyme prerequisite for metabolism of unsaturated oligosaccharides produced by polysaccharide lyases. | Hashimoto W, Kobayashi E, Nankai H, Sato N, Miya T, Kawai S, Murata K | 1999 Aug 15 | 10441389 |