EC number:3.2.2.1
| ID: | 3.2.2.1 |
|---|---|
| Description: | Purine nucleosidase. |
| Alternative Name: |
Ribonucleoside hydrolase. Purine-specific nucleoside N-ribohydrolase. Purine ribonucleosidase. Purine nucleoside hydrolase. Purine beta-ribosidase. Nucleoside hydrolase. Nucleosidase g. Nucleosidase. N-ribosyl purine ribohydrolase. N-D-ribosylpurine ribohydrolase. Inosine-adenosine-guanosine preferring nucleoside hydrolase. IAG-nucleoside hydrolase. IAG-NH. |
| Prosite: | PDOC00960; |
| PDB: |
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| Cath: | 3.90.245.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.2.2.1 |
| BRENDA Enzyme Link: | BRENDA 3.2.2.1 |
| KEGG Enzyme Link: | KEGG3.2.2.1 |
| BioCyc Enzyme Link: | BioCyc 3.2.2.1 |
| ExPASy Enzyme Link: | ExPASy3.2.2.1 |
| EC2PDB Enzyme Link: | EC2PDB 3.2.2.1 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.2.2.1 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.2.2.1 |
| IntEnz Enzyme Link: | IntEnz 3.2.2.1 |
| MEDLINE Enzyme Link: | MEDLINE 3.2.2.1 |
| RHEA:23344 | a purine ribonucleoside + H2O = a purine base + D-ribose |
| RULE(radius=1) | [*:1]:[n;H0;+0:2](:[*:3])-[CH;+0:4](-[*:5])-[*:6].[OH2;+0:7]>>[*:5]-[CH;+0:4](-[*:6])-[OH;+0:7].[*:1]:[nH;+0:2]:[*:3] |
| Reaction |  |
| Core-to-Core | |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purine-specific nucleoside N-ribohydrolase from Trypanosoma brucei brucei. Purification, specificity, and kinetic mechanism. | Parkin DW | 1996 Sep 6 | 8702965 |
| Examination of the mechanism and energetic contribution of leaving group activation in the purine-specific nucleoside hydrolase from Trypanosoma vivax. | Barlow JN, Steyaert J | 2007 Nov | 17936095 |
| Transition-state complex of the purine-specific nucleoside hydrolase of T. vivax: enzyme conformational changes and implications for catalysis. | Versées W, Barlow J, Steyaert J | 2006 Jun 2 | 16630632 |
| Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax. | Versées W, Decanniere K, Van Holsbeke E, Devroede N, Steyaert J | 2002 May 3 | 11854281 |
| Purification, characterization, and gene cloning of purine nucleosidase from Ochrobactrum anthropi. | Ogawa J, Takeda S, Xie SX, Hatanaka H, Ashikari T, Amachi T, Shimizu S | 2001 Apr | 11282633 |