EC number:3.3.2.2
| ID: | 3.3.2.2 |
|---|---|
| Description: | Lysoplasmalogenase. |
| Alternative Name: |
Alkenylglycerophosphoethanolamine hydrolase. Alkenylglycerophosphocholine hydrolase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.3.2.2 |
| BRENDA Enzyme Link: | BRENDA 3.3.2.2 |
| KEGG Enzyme Link: | KEGG3.3.2.2 |
| BioCyc Enzyme Link: | BioCyc 3.3.2.2 |
| ExPASy Enzyme Link: | ExPASy3.3.2.2 |
| EC2PDB Enzyme Link: | EC2PDB 3.3.2.2 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.3.2.2 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.3.2.2 |
| IntEnz Enzyme Link: | IntEnz 3.3.2.2 |
| MEDLINE Enzyme Link: | MEDLINE 3.3.2.2 |
| RHEA:22544 | 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + H2O = a 2,3-saturated aldehyde + sn-glycerol 3-phosphocholine |
| RULE(radius=1) | [*:1]-[CH;+0:2]=[CH;+0:3]-[O;H0;+0:4]-[*:5].[OH2;+0:6]>>[*:1]-[CH2;+0:2]-[CH;+0:3]=[O;H0;+0:6].[*:5]-[OH;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification, identification, and cloning of lysoplasmalogenase, the enzyme that catalyzes hydrolysis of the vinyl ether bond of lysoplasmalogen. | Wu LC, Pfeiffer DR, Calhoon EA, Madiai F, Marcucci G, Liu S, Jurkowitz MS | 2011 Jul 15 | 21515882 |
| The catabolism of plasmenylcholine in the guinea pig heart. | Arthur G, Page L, Mock T, Choy PC | 1986 Jun 1 | 3753461 |
| The metabolism of plasmalogen: enzymatic hydrolysis of the vinyl ether. | WARNER HR, LANDS WE | 1961 Sep | 13783189 |
| RHEA:16905 | 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O = a 2,3-saturated aldehyde + sn-glycero-3-phosphoethanolamine |
| RULE(radius=1) | [*:1]-[CH;+0:2]=[CH;+0:3]-[O;H0;+0:4]-[*:5].[OH2;+0:6]>>[*:1]-[CH2;+0:2]-[CH;+0:3]=[O;H0;+0:6].[*:5]-[OH;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Liberation of free aldehyde from 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine (lysoplasmalogen) by rat liver microsomes. | Gunawan J, Debuch H | 1981 Apr | 7239443 |
| Purification, identification, and cloning of lysoplasmalogenase, the enzyme that catalyzes hydrolysis of the vinyl ether bond of lysoplasmalogen. | Wu LC, Pfeiffer DR, Calhoon EA, Madiai F, Marcucci G, Liu S, Jurkowitz MS | 2011 Jul 15 | 21515882 |