| ID: | 3.3.2.7 |
|---|---|
| Description: | Hepoxilin-epoxide hydrolase. |
| Alternative Name: |
Hepoxylin hydrolase. Hepoxilin epoxide hydrolase. Hepoxilin A(3) hydrolase. |
| Cath: | 3.10.450.50; |
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.| UniProtKB Enzyme Link: | UniProtKB 3.3.2.7 |
| BRENDA Enzyme Link: | BRENDA 3.3.2.7 |
| KEGG Enzyme Link: | KEGG3.3.2.7 |
| BioCyc Enzyme Link: | BioCyc 3.3.2.7 |
| ExPASy Enzyme Link: | ExPASy3.3.2.7 |
| EC2PDB Enzyme Link: | EC2PDB 3.3.2.7 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.3.2.7 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.3.2.7 |
| IntEnz Enzyme Link: | IntEnz 3.3.2.7 |
| MEDLINE Enzyme Link: | MEDLINE 3.3.2.7 |
| RHEA:16665 | (5Z,9E,14Z)-(8xi,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate + H2O = (5Z,9E,14Z)-(8xi,11xi,12S)-8,11,12-trihydroxyicosa-5,9,14-trienoate |
| RULE(radius=1) | [*:1]-[CH;+0:2]1-[*:3]-[O;H0;+0:4]-1.[OH2;+0:5]>>[*:1]-[CH;+0:2](-[OH;+0:5])-[*:3]-[OH;+0:4] |
| Reaction | ![]() |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Formation and metabolism of hepoxilin A3 by the rat brain. | Pace-Asciak CR | 1988 Feb 29 | 3348791 |
| Purification of hepoxilin epoxide hydrolase from rat liver. | Pace-Asciak CR, Lee WS | 1989 Jun 5 | 2722835 |
| Epoxide hydrolases: their roles and interactions with lipid metabolism. | Newman JW, Morisseau C, Hammock BD | 2005 Jan | 15748653 |
| Epoxide hydrolases: biochemistry and molecular biology. | Fretland AJ, Omiecinski CJ | 2000 Dec 1 | 11154734 |