EC number:3.5.1.100
Enzyme
Download| EC Tree |
| 3. Hydrolases |
| 3.5 Acting on carbon-nitrogen bonds, other than peptide bonds |
| 3.5.1 In linear amides |
| ID: | 3.5.1.100 | ||
|---|---|---|---|
| Description: | (R)-amidase. | ||
| Alternative Name: |
R-stereospecific amidase. R-amidase. | ||
| Prosite: | PDOC50263; | ||
| PDB: |
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| Cath: | 3.60.110.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.5.1.100 |
| BRENDA Enzyme Link: | BRENDA 3.5.1.100 |
| KEGG Enzyme Link: | KEGG3.5.1.100 |
| BioCyc Enzyme Link: | BioCyc 3.5.1.100 |
| ExPASy Enzyme Link: | ExPASy3.5.1.100 |
| EC2PDB Enzyme Link: | EC2PDB 3.5.1.100 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.5.1.100 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.5.1.100 |
| IntEnz Enzyme Link: | IntEnz 3.5.1.100 |
| MEDLINE Enzyme Link: | MEDLINE 3.5.1.100 |
EC number:3.5.1.100
| MSA: | |
|---|---|
| Phylogenetic Tree: | |
| Uniprot: | |
| M-CSA: |
| RHEA:26542 | (R)-piperazine-2-carboxamide + H2O = (R)-piperazine-2-carboxylate + NH4(+) |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[*:3])-[NH2;+0:4].[OH2;+0:5]>>[*:1]=[C;H0;+0:2](-[*:3])-[OH;+0:5].[NH3;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A novel R-stereoselective amidase from Pseudomonas sp. MCI3434 acting on piperazine-2-tert-butylcarboxamide. | Komeda H, Harada H, Washika S, Sakamoto T, Ueda M, Asano Y | 2004 Apr | 15066183 |
| RHEA:26546 | beta-alaninamide + H2O = beta-alanine + NH4(+) |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[*:3])-[NH2;+0:4].[OH2;+0:5]>>[*:1]=[C;H0;+0:2](-[*:3])-[OH;+0:5].[NH3;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A novel R-stereoselective amidase from Pseudomonas sp. MCI3434 acting on piperazine-2-tert-butylcarboxamide. | Komeda H, Harada H, Washika S, Sakamoto T, Ueda M, Asano Y | 2004 Apr | 15066183 |
| RHEA:27574 | (3R)-piperidine-3-carboxamide + H2O = (3R)-piperidine-3-carboxylate + NH4(+) |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[*:3])-[NH2;+0:4].[OH2;+0:5]>>[*:1]=[C;H0;+0:2](-[*:3])-[OH;+0:5].[NH3;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A novel R-stereoselective amidase from Pseudomonas sp. MCI3434 acting on piperazine-2-tert-butylcarboxamide. | Komeda H, Harada H, Washika S, Sakamoto T, Ueda M, Asano Y | 2004 Apr | 15066183 |
| RHEA:27578 | (R)-N-tert-butylpiperazine-2-carboxamide + H2O = (R)-piperazine-2-carboxylate + tert-butylamine |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[*:3])-[NH;+0:4]-[*:5].[OH2;+0:6]>>[*:5]-[NH2;+0:4].[*:1]=[C;H0;+0:2](-[*:3])-[OH;+0:6] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A novel R-stereoselective amidase from Pseudomonas sp. MCI3434 acting on piperazine-2-tert-butylcarboxamide. | Komeda H, Harada H, Washika S, Sakamoto T, Ueda M, Asano Y | 2004 Apr | 15066183 |