EC number:3.5.1.128

Enzyme

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EC Tree
     3. Hydrolases
        3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
            3.5.1 In linear amides
ID:3.5.1.128
Description:Deaminated glutathione amidase.
Alternative Name: DGSH deaminase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 3.5.1.128
BRENDA Enzyme Link: BRENDA 3.5.1.128
KEGG Enzyme Link: KEGG3.5.1.128
BioCyc Enzyme Link: BioCyc 3.5.1.128
ExPASy Enzyme Link: ExPASy3.5.1.128
EC2PDB Enzyme Link: EC2PDB 3.5.1.128
ExplorEnz Enzyme Link: ExplorEnz 3.5.1.128
PRIAM enzyme-specific profiles Link: PRIAM 3.5.1.128
IntEnz Enzyme Link: IntEnz 3.5.1.128
MEDLINE Enzyme Link: MEDLINE 3.5.1.128

EC number:3.5.1.128

MSA:

3.5.1.128;
Phylogenetic Tree:

3.5.1.128;
Uniprot:
M-CSA:
RHEA:54532 H2O + N-(4-oxoglutaryl)-L-cysteinylglycine = 2-oxoglutarate + L-cysteinylglycine
RULE(radius=1) [*:1]-[NH;+0:2]-[C;H0;+0:3](-[*:4])=[*:5].[OH2;+0:6]>>[*:4]-[C;H0;+0:3](=[*:5])-[OH;+0:6].[*:1]-[NH2;+0:2]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Nit1 is a metabolite repair enzyme that hydrolyzes deaminated glutathione.Peracchi A, Veiga-da-Cunha M, Kuhara T, Ellens KW, Paczia N, Stroobant V, Seliga AK, Marlaire S, Jaisson S, Bommer GT, Sun J, Huebner K, Linster CL, Cooper AJL, Van Schaftingen E2017 Apr 1828373563