EC number:3.5.1.36
Enzyme
Download| EC Tree |
| 3. Hydrolases |
| 3.5 Acting on carbon-nitrogen bonds, other than peptide bonds |
| 3.5.1 In linear amides |
| ID: | 3.5.1.36 |
|---|---|
| Description: | N-methyl-2-oxoglutaramate hydrolase. |
| Alternative Name: |
5-hydroxy-N-methylpyroglutamate synthase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.5.1.36 |
| BRENDA Enzyme Link: | BRENDA 3.5.1.36 |
| KEGG Enzyme Link: | KEGG3.5.1.36 |
| BioCyc Enzyme Link: | BioCyc 3.5.1.36 |
| ExPASy Enzyme Link: | ExPASy3.5.1.36 |
| EC2PDB Enzyme Link: | EC2PDB 3.5.1.36 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.5.1.36 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.5.1.36 |
| IntEnz Enzyme Link: | IntEnz 3.5.1.36 |
| MEDLINE Enzyme Link: | MEDLINE 3.5.1.36 |
| RHEA:24108 | H2O + N-methyl-2-oxoglutaramate = 2-oxoglutarate + methylamine |
| RULE(radius=1) | [*:1]-[NH;+0:2]-[C;H0;+0:3](-[*:4])=[*:5].[OH2;+0:6]>>[*:4]-[C;H0;+0:3](=[*:5])-[OH;+0:6].[*:1]-[NH2;+0:2] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The enzymatic synthesis of 5-hydroxy-N-methylpyroglutamic acid. | Hersh LB, Tsai L, Stadtman ER | 1969 Sep 10 | 5808511 |
| 5-hydroxy-N-methylpyroglutamate synthetase. Purification and mechanism of action. | Hersh LB | 1970 Jul 25 | 5470822 |