EC number:3.5.1.44

Enzyme

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EC Tree
     3. Hydrolases
        3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
            3.5.1 In linear amides
ID:3.5.1.44
Description:Protein-glutamine glutaminase.
Alternative Name: Peptidoglutaminase II.
Glutaminylpeptide glutaminase.
Cath: 3.30.1330.20; 3.30.1330.200; 3.90.550.20;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 3.5.1.44
BRENDA Enzyme Link: BRENDA 3.5.1.44
KEGG Enzyme Link: KEGG3.5.1.44
BioCyc Enzyme Link: BioCyc 3.5.1.44
ExPASy Enzyme Link: ExPASy3.5.1.44
EC2PDB Enzyme Link: EC2PDB 3.5.1.44
ExplorEnz Enzyme Link: ExplorEnz 3.5.1.44
PRIAM enzyme-specific profiles Link: PRIAM 3.5.1.44
IntEnz Enzyme Link: IntEnz 3.5.1.44
MEDLINE Enzyme Link: MEDLINE 3.5.1.44

EC number:3.5.1.44

MSA:

3.5.1.44;
Phylogenetic Tree:

3.5.1.44;
Uniprot:
M-CSA:
RHEA:16441 H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+)
RULE(radius=1) [*:1]=[C;H0;+0:2](-[*:3])-[NH2;+0:4].[OH2;+0:5]>>[*:1]=[C;H0;+0:2](-[*:3])-[OH;+0:5].[NH3;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Peptidoglutaminase. Enzymes for selective deamidation of gamma-amide of peptide-bound glutamine.Kikuchi M, Hayashida H, Nakano E, Sakaguchi K1971 Mar 304928623
Species-Specific Deamidation of cGAS by Herpes Simplex Virus UL37 Protein Facilitates Viral Replication.Zhang J, Zhao J, Xu S, Li J, He S, Zeng Y, Xie L, Xie N, Liu T, Lee K, Seo GJ, Chen L, Stabell AC, Xia Z, Sawyer SL, Jung J, Huang C, Feng P2018 Aug 830092200