EC number:3.5.1.46
Enzyme
Download| EC Tree |
| 3. Hydrolases |
| 3.5 Acting on carbon-nitrogen bonds, other than peptide bonds |
| 3.5.1 In linear amides |
| ID: | 3.5.1.46 |
|---|---|
| Description: | 6-aminohexanoate-oligomer exohydrolase. |
| Alternative Name: |
Nylon-6 hydrolase. 6-aminohexanoic acid oligomer hydrolase. 6-aminohexanoate-dimer hydrolase. |
| Cath: | 1.20.5.1730; 3.40.710.10; 1.20.58.710; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.5.1.46 |
| BRENDA Enzyme Link: | BRENDA 3.5.1.46 |
| KEGG Enzyme Link: | KEGG3.5.1.46 |
| BioCyc Enzyme Link: | BioCyc 3.5.1.46 |
| ExPASy Enzyme Link: | ExPASy3.5.1.46 |
| EC2PDB Enzyme Link: | EC2PDB 3.5.1.46 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.5.1.46 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.5.1.46 |
| IntEnz Enzyme Link: | IntEnz 3.5.1.46 |
| MEDLINE Enzyme Link: | MEDLINE 3.5.1.46 |
| RHEA:21364 | H2O + N-(6-aminohexanoyl)-6-aminohexanoate = 2 6-aminohexanoate |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[*:3])-[NH;+0:4]-[*:5].[OH2;+0:6]>>[*:5]-[NH2;+0:4].[*:1]=[C;H0;+0:2](-[*:3])-[OH;+0:6] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and characterization of 6-aminohexanoic-acid-oligomer hydrolase of Flavobacterium sp. Ki72. | Kinoshita S, Terada T, Taniguchi T, Takene Y, Masuda S, Matsunaga N, Okada H | 1981 Jun 1 | 7262074 |
| Mutational analysis of 6-aminohexanoate-dimer hydrolase: relationship between nylon oligomer hydrolytic and esterolytic activities. | Ohki T, Wakitani Y, Takeo M, Yasuhira K, Shibata N, Higuchi Y, Negoro S | 2006 Sep 18 | 16949580 |
| Crystallization and X-ray diffraction analysis of 6-aminohexanoate-dimer hydrolase from Arthrobacter sp. KI72. | Ohki T, Mizuno N, Shibata N, Takeo M, Negoro S, Higuchi Y | 2005 Oct 1 | 16511198 |
| X-ray crystallographic analysis of 6-aminohexanoate-dimer hydrolase: molecular basis for the birth of a nylon oligomer-degrading enzyme. | Negoro S, Ohki T, Shibata N, Mizuno N, Wakitani Y, Tsurukame J, Matsumoto K, Kawamoto I, Takeo M, Higuchi Y | 2005 Nov 25 | 16162506 |