EC number:3.5.1.54
Enzyme
Download| EC Tree |
| 3. Hydrolases |
| 3.5 Acting on carbon-nitrogen bonds, other than peptide bonds |
| 3.5.1 In linear amides |
| ID: | 3.5.1.54 |
|---|---|
| Description: | Allophanate hydrolase. |
| Cath: | 3.10.490.10; 3.30.1330.160; 3.30.1330.170; 3.30.1330.180; 3.30.1360.40; 3.90.1300.10; 1.20.58.1700; 2.40.100.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.5.1.54 |
| BRENDA Enzyme Link: | BRENDA 3.5.1.54 |
| KEGG Enzyme Link: | KEGG3.5.1.54 |
| BioCyc Enzyme Link: | BioCyc 3.5.1.54 |
| ExPASy Enzyme Link: | ExPASy3.5.1.54 |
| EC2PDB Enzyme Link: | EC2PDB 3.5.1.54 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.5.1.54 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.5.1.54 |
| IntEnz Enzyme Link: | IntEnz 3.5.1.54 |
| MEDLINE Enzyme Link: | MEDLINE 3.5.1.54 |
| RHEA:19029 | 3 H(+) + H2O + urea-1-carboxylate = 2 CO2 + 2 NH4(+) |
| RULE(radius=1) | [*:1]=[C;H0;+0:2](-[OH;+0:3])-[NH;+0:4]-[C;H0;+0:5](=[*:6])-[NH2;+0:7].[H+;H0:8].[H+;H0:9].[H+;H0:10].[OH2;+0:11]>>[*:1]=[C;H0;+0:2]=[O;H0;+0:3].[*:6]=[C;H0;+0:5]=[O;H0;+0:11].[NH3;+0:7].[NH3;+0:4] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A second pathway to degrade pyrimidine nucleic acid precursors in eukaryotes. | Andersen G, Björnberg O, Polakova S, Pynyaha Y, Rasmussen A, Møller K, Hofer A, Moritz T, Sandrini MP, Merico AM, Compagno C, Akerlund HE, Gojković Z, Piskur J | 2008 Jul 18 | 18550080 |
| Purification and characterization of TrzF: biuret hydrolysis by allophanate hydrolase supports growth. | Shapir N, Cheng G, Sadowsky MJ, Wackett LP | 2006 Apr | 16597948 |
| Allophanate hydrolase, not urease, functions in bacterial cyanuric acid metabolism. | Cheng G, Shapir N, Sadowsky MJ, Wackett LP | 2005 Aug | 16085834 |
| Purification and characterization of allophanate hydrolase (AtzF) from Pseudomonas sp. strain ADP. | Shapir N, Sadowsky MJ, Wackett LP | 2005 Jun | 15901697 |
| Allophanate hydrolase of Oleomonas sagaranensis involved in an ATP-dependent degradation pathway specific to urea. | Kanamori T, Kanou N, Kusakabe S, Atomi H, Imanaka T | 2005 Apr 1 | 15796980 |
| Complete nucleotide sequence and organization of the atrazine catabolic plasmid pADP-1 from Pseudomonas sp. strain ADP. | Martinez B, Tomkins J, Wackett LP, Wing R, Sadowsky MJ | 2001 Oct | 11544232 |