EC number:3.5.1.66

Enzyme

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EC Tree
     3. Hydrolases
        3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
            3.5.1 In linear amides
ID:3.5.1.66
Description:2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 3.5.1.66
BRENDA Enzyme Link: BRENDA 3.5.1.66
KEGG Enzyme Link: KEGG3.5.1.66
BioCyc Enzyme Link: BioCyc 3.5.1.66
ExPASy Enzyme Link: ExPASy3.5.1.66
EC2PDB Enzyme Link: EC2PDB 3.5.1.66
ExplorEnz Enzyme Link: ExplorEnz 3.5.1.66
PRIAM enzyme-specific profiles Link: PRIAM 3.5.1.66
IntEnz Enzyme Link: IntEnz 3.5.1.66
MEDLINE Enzyme Link: MEDLINE 3.5.1.66

EC number:3.5.1.66

MSA:

3.5.1.66;
Phylogenetic Tree:

3.5.1.66;
Uniprot:
M-CSA:
RHEA:17677 2-(acetamidomethylene)-3-(hydroxymethyl)succinate + H(+) + 2 H2O = 2-(hydroxymethyl)-4-oxobutanoate + acetate + CO2 + NH4(+)
RULE(radius=1) [*:1]-[C;H0;+0:2](=[CH;+0:3]-[NH;+0:4]-[C;H0;+0:5](=[*:6])-[*:7])-[C;H0;+0:8](=[*:9])-[OH;+0:10].[H+;H0:11].[OH2;+0:12].[OH2;+0:13]>>[*:1]-[CH2;+0:2]-[CH;+0:3]=[O;H0;+0:13].[*:6]=[C;H0;+0:5](-[*:7])-[OH;+0:12].[*:9]=[C;H0;+0:8]=[O;H0;+0:10].[NH3;+0:4]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Enzymes of vitamin B6 degradation. Purification and properties of two N-acetylamidohydrolases.Huynh MS, Snell EE1985 Feb 253972793