EC number:3.5.2.14

Enzyme

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     3. Hydrolases
        3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
            3.5.2 In cyclic amides
ID:3.5.2.14
Description:N-methylhydantoinase (ATP-hydrolyzing).
Alternative Name: N-methylhydantoin amidohydrolase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 3.5.2.14
BRENDA Enzyme Link: BRENDA 3.5.2.14
KEGG Enzyme Link: KEGG3.5.2.14
BioCyc Enzyme Link: BioCyc 3.5.2.14
ExPASy Enzyme Link: ExPASy3.5.2.14
EC2PDB Enzyme Link: EC2PDB 3.5.2.14
ExplorEnz Enzyme Link: ExplorEnz 3.5.2.14
PRIAM enzyme-specific profiles Link: PRIAM 3.5.2.14
IntEnz Enzyme Link: IntEnz 3.5.2.14
MEDLINE Enzyme Link: MEDLINE 3.5.2.14

EC number:3.5.2.14

MSA:

3.5.2.14;
Phylogenetic Tree:

3.5.2.14;
Uniprot:
M-CSA:
RHEA:11720 ATP + 2 H2O + N-methylhydantoin = ADP + 2 H(+) + N-carbamoylsarcosine + phosphate
RULE(radius=1) ([*:1]-[NH2;+0:2].[*:3]=[C;H0;+0:4](-[*:5])-[OH;+0:6]).[*:7]-[OH;+0:8].[*:9]=[P;H0;+0:10](-[*:11])(-[*:12])-[OH;+0:13].[H+;H0:14].[H+;H0:15]>>[*:7]-[O;H0;+0:8]-[P;H0;+0:10](=[*:9])(-[*:11])-[*:12].[*:3]=[C;H0;+0:4](-[*:5])-[NH;+0:2]-[*:1].[OH2;+0:6].[OH2;+0:13]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Amidohydrolysis of N-methylhydantoin coupled with ATP hydrolysis.Kim JM, Shimizu S, Yamada H1987 Feb 133827889