EC number:3.5.4.25
Enzyme
Download| EC Tree |
| 3. Hydrolases |
| 3.5 Acting on carbon-nitrogen bonds, other than peptide bonds |
| 3.5.4 In cyclic amidines |
| ID: | 3.5.4.25 |
|---|---|
| Description: | GTP cyclohydrolase II. |
| Cath: | 3.30.70.1230; 3.30.70.270; 3.90.870.10; 3.40.140.10; 3.40.430.10; 3.40.50.10990; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.5.4.25 |
| BRENDA Enzyme Link: | BRENDA 3.5.4.25 |
| KEGG Enzyme Link: | KEGG3.5.4.25 |
| BioCyc Enzyme Link: | BioCyc 3.5.4.25 |
| ExPASy Enzyme Link: | ExPASy3.5.4.25 |
| EC2PDB Enzyme Link: | EC2PDB 3.5.4.25 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.5.4.25 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.5.4.25 |
| IntEnz Enzyme Link: | IntEnz 3.5.4.25 |
| MEDLINE Enzyme Link: | MEDLINE 3.5.4.25 |
| RHEA:23704 | GTP + 3 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + diphosphate + formate + 2 H(+) |
| RULE(radius=1) | [*:1]:[nH;+0:2]:[c;H0;+0:3](=[O;H0;+0:4]):[*:5]1:[*:6]:[n;H0;+0:7](-[CH3;+0:8]):[cH;+0:9]:[n;H0;+0:10]:1.[OH2;+0:11].[OH2;+0:12]>>[*:1]:[n;H0;+0:2]:[c;H0;+0:3](-[OH;+0:4]):[*:5](-[NH2;+0:10]):[*:6]-[NH;+0:7]-[CH3;+0:9].[O;H0;+0:12]=[CH;+0:8]-[OH;+0:11] |
| Reaction |  |
| Core-to-Core |