EC number:3.5.4.33
Enzyme
Download| EC Tree |
| 3. Hydrolases |
| 3.5 Acting on carbon-nitrogen bonds, other than peptide bonds |
| 3.5.4 In cyclic amidines |
| ID: | 3.5.4.33 |
|---|---|
| Description: | tRNA(adenine(34)) deaminase. |
| Cath: | 3.40.140.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.5.4.33 |
| BRENDA Enzyme Link: | BRENDA 3.5.4.33 |
| KEGG Enzyme Link: | KEGG3.5.4.33 |
| BioCyc Enzyme Link: | BioCyc 3.5.4.33 |
| ExPASy Enzyme Link: | ExPASy3.5.4.33 |
| EC2PDB Enzyme Link: | EC2PDB 3.5.4.33 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.5.4.33 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.5.4.33 |
| IntEnz Enzyme Link: | IntEnz 3.5.4.33 |
| MEDLINE Enzyme Link: | MEDLINE 3.5.4.33 |
| RHEA:43168 | adenosine(34) in tRNA + H(+) + H2O = inosine(34) in tRNA + NH4(+) |
| RULE(radius=1) | [*:1]-[n;H0;+0:2]1:[cH;+0:3]:[n;H0;+0:4]:[c;H0;+0:5]2:[c;H0;+0:6](-[NH2;+0:7]):[n;H0;+0:8]:[cH;+0:9]:[n;H0;+0:10]:[c;H0;+0:11]:2:1.[H+;H0:12].[OH2;+0:13]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[N;H0;+0:4]-[CH;+0:5]2-[C;H0;+0:6](=[O;H0;+0:13])-[N;H0;+0:8]=[CH;+0:9]-[N;H0;+0:10]=[C;H0;+0:11]-2-1.[NH3;+0:7] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| A single zinc ion is sufficient for an active Trypanosoma brucei tRNA editing deaminase. | Spears JL, Rubio MA, Gaston KW, Wywial E, Strikoudis A, Bujnicki JM, Papavasiliou FN, Alfonzo JD | 2011 Jun 10 | 21507956 |
| Arabidopsis tRNA adenosine deaminase arginine edits the wobble nucleotide of chloroplast tRNAArg(ACG) and is essential for efficient chloroplast translation. | Delannoy E, Le Ret M, Faivre-Nitschke E, Estavillo GM, Bergdoll M, Taylor NL, Pogson BJ, Small I, Imbault P, Gualberto JM | 2009 Jul | 19602623 |
| Crystal structure of tRNA adenosine deaminase (TadA) from Aquifex aeolicus. | Kuratani M, Ishii R, Bessho Y, Fukunaga R, Sengoku T, Shirouzu M, Sekine S, Yokoyama S | 2005 Apr 22 | 15677468 |