EC number:3.5.4.34
Enzyme
Download| EC Tree |
| 3. Hydrolases |
| 3.5 Acting on carbon-nitrogen bonds, other than peptide bonds |
| 3.5.4 In cyclic amidines |
| ID: | 3.5.4.34 |
|---|---|
| Description: | tRNA(Ala)(adenine(37)) deaminase. |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.5.4.34 |
| BRENDA Enzyme Link: | BRENDA 3.5.4.34 |
| KEGG Enzyme Link: | KEGG3.5.4.34 |
| BioCyc Enzyme Link: | BioCyc 3.5.4.34 |
| ExPASy Enzyme Link: | ExPASy3.5.4.34 |
| EC2PDB Enzyme Link: | EC2PDB 3.5.4.34 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.5.4.34 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.5.4.34 |
| IntEnz Enzyme Link: | IntEnz 3.5.4.34 |
| MEDLINE Enzyme Link: | MEDLINE 3.5.4.34 |
| RHEA:50968 | adenosine(37) in tRNA(Ala) + H(+) + H2O = inosine(37) in tRNA(Ala) + NH4(+) |
| RULE(radius=1) | [*:1]-[n;H0;+0:2]1:[cH;+0:3]:[n;H0;+0:4]:[c;H0;+0:5]2:[c;H0;+0:6](-[NH2;+0:7]):[n;H0;+0:8]:[cH;+0:9]:[n;H0;+0:10]:[c;H0;+0:11]:2:1.[H+;H0:12].[OH2;+0:13]>>[*:1]-[N;H0;+0:2]1-[CH;+0:3]=[N;H0;+0:4]-[CH;+0:5]2-[C;H0;+0:6](=[O;H0;+0:13])-[N;H0;+0:8]=[CH;+0:9]-[N;H0;+0:10]=[C;H0;+0:11]-2-1.[NH3;+0:7] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Tad1p, a yeast tRNA-specific adenosine deaminase, is related to the mammalian pre-mRNA editing enzymes ADAR1 and ADAR2. | Gerber A, Grosjean H, Melcher T, Keller W | 1998 Aug 17 | 9707437 |
| Sequence, genomic organization and functional expression of the murine tRNA-specific adenosine deaminase ADAT1. | Maas S, Kim YG, Rich A | 2000 Feb 8 | 10675613 |
| The properties of a tRNA-specific adenosine deaminase from Drosophila melanogaster support an evolutionary link between pre-mRNA editing and tRNA modification. | Keegan LP, Gerber AP, Brindle J, Leemans R, Gallo A, Keller W, O'Connell MA | 2000 Feb | 10629039 |
| Identification and characterization of a human tRNA-specific adenosine deaminase related to the ADAR family of pre-mRNA editing enzymes. | Maas S, Gerber AP, Rich A | 1999 Aug 3 | 10430867 |