EC number:3.5.4.43

Enzyme

Download
EC Tree
     3. Hydrolases
        3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
            3.5.4 In cyclic amidines
ID:3.5.4.43
Description:Hydroxydechloroatrazine ethylaminohydrolase.
Alternative Name: Hydroxyatrazine hydrolase.
2,4-dihydroxy-6-(isopropylamino)-1,3,5-triazine ethylaminohydrolase.

3D structure

Click one PDB to see exact 3D structure provided by NGL.

Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.
PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 3.5.4.43
BRENDA Enzyme Link: BRENDA 3.5.4.43
KEGG Enzyme Link: KEGG3.5.4.43
BioCyc Enzyme Link: BioCyc 3.5.4.43
ExPASy Enzyme Link: ExPASy3.5.4.43
EC2PDB Enzyme Link: EC2PDB 3.5.4.43
ExplorEnz Enzyme Link: ExplorEnz 3.5.4.43
PRIAM enzyme-specific profiles Link: PRIAM 3.5.4.43
IntEnz Enzyme Link: IntEnz 3.5.4.43
MEDLINE Enzyme Link: MEDLINE 3.5.4.43

EC number:3.5.4.43

MSA:

3.5.4.43;
Phylogenetic Tree:

3.5.4.43;
Uniprot:
M-CSA:
RHEA:23092 H(+) + H2O + hydroxyatrazine = ethylamine + N-isopropylammelide
RULE(radius=1) [*:1]-[NH;+0:2]-[c;H0;+0:3](:[*:4]):[*:5].[H+;H0:6].[OH2;+0:7]>>[*:1]-[NH2;+0:2].[*:4]:[c;H0;+0:3](:[*:5])-[OH;+0:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Atrazine chlorohydrolase from Pseudomonas sp. strain ADP is a metalloenzyme.Seffernick JL, McTavish H, Osborne JP, de Souza ML, Sadowsky MJ, Wackett LP2002 Dec 312450410
The atzB gene of Pseudomonas sp. strain ADP encodes the second enzyme of a novel atrazine degradation pathway.Boundy-Mills KL, de Souza ML, Mandelbaum RT, Wackett LP, Sadowsky MJ1997 Mar9055410
Hydroxyatrazine N-ethylaminohydrolase (AtzB): an amidohydrolase superfamily enzyme catalyzing deamination and dechlorination.Seffernick JL, Aleem A, Osborne JP, Johnson G, Sadowsky MJ, Wackett LP2007 Oct17660279