Enzyme

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     3. Hydrolases
        3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
            3.5.4 In cyclic amidines
ID:3.5.4.9
Description:Methenyltetrahydrofolate cyclohydrolase.
Prosite: PDOC00616;
PDB:
PDBScop
Cath: 1.10.8.770; 3.30.1510.10; 3.40.50.720; 3.40.50.10860; 3.40.50.300; 3.10.410.10;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.5.4.9
BRENDA Enzyme Link: BRENDA 3.5.4.9
KEGG Enzyme Link: KEGG3.5.4.9
BioCyc Enzyme Link: BioCyc 3.5.4.9
ExPASy Enzyme Link: ExPASy3.5.4.9
EC2PDB Enzyme Link: EC2PDB 3.5.4.9
ExplorEnz Enzyme Link: ExplorEnz 3.5.4.9
PRIAM enzyme-specific profiles Link: PRIAM 3.5.4.9
IntEnz Enzyme Link: IntEnz 3.5.4.9
MEDLINE Enzyme Link: MEDLINE 3.5.4.9
MSA:

3.5.4.9;

Phylogenetic Tree:

3.5.4.9;

Uniprot:
M-CSA:
RHEA:23700 5,10-methenyltetrahydrofolate + H2O = (6S)-10-formyltetrahydrofolate + H(+)
RULE(radius=1) [*:1]-[CH;+0:2]=[N+;H0:3](-[*:4])-[*:5].[OH2;+0:6]>>([*:1]-[CH;+0:2]=[O;H0;+0:6].[*:4]-[NH;+0:3]-[*:5])
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References

TitleAuthorsDatePubMed ID
The enzymatic formation of formiminotetrahydrofolic acid, 5,10-methenyltetrahydrofolic acid, and 10-formyltetrahydrofolic acid in the metabolism of formiminoglutamic acid.TABOR H, WYNGARDEN L1959 Jul13672973