EC number:3.5.5.5

Enzyme

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     3. Hydrolases
        3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
            3.5.5 In nitriles
ID:3.5.5.5
Description:Arylacetonitrilase.

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 3.5.5.5
BRENDA Enzyme Link: BRENDA 3.5.5.5
KEGG Enzyme Link: KEGG3.5.5.5
BioCyc Enzyme Link: BioCyc 3.5.5.5
ExPASy Enzyme Link: ExPASy3.5.5.5
EC2PDB Enzyme Link: EC2PDB 3.5.5.5
ExplorEnz Enzyme Link: ExplorEnz 3.5.5.5
PRIAM enzyme-specific profiles Link: PRIAM 3.5.5.5
IntEnz Enzyme Link: IntEnz 3.5.5.5
MEDLINE Enzyme Link: MEDLINE 3.5.5.5

EC number:3.5.5.5

MSA:

3.5.5.5;
Phylogenetic Tree:

3.5.5.5;
Uniprot:
M-CSA:
RHEA:20657 4-chlorophenylacetonitrile + 2 H2O = 4-chlorophenylacetate + NH4(+)
RULE(radius=1) [*:1]-[C;H0;+0:2]#[N;H0;+0:3].[OH2;+0:4].[OH2;+0:5]>>[*:1]-[C;H0;+0:2](=[O;H0;+0:5])-[OH;+0:4].[NH3;+0:3]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
A comparative study of nitrilases identified by genome mining.Kaplan O, Veselá AB, Petříčková A, Pasquarelli F, Pičmanová M, Rinágelová A, Bhalla TC, Pátek M, Martínková L2013 Jul23475593
A novel nitrilase, arylacetonitrilase, of Alcaligenes faecalis JM3. Purification and characterization.Nagasawa T, Mauger J, Yamada H1990 Dec 272269298
Purification and characterization of heterologously expressed nitrilases from filamentous fungi.Petříčková A, Veselá AB, Kaplan O, Kubáč D, Uhnáková B, Malandra A, Felsberg J, Rinágelová A, Weyrauch P, Křen V, Bezouška K, Martínková L2012 Feb21892598
Genome mining for the discovery of new nitrilases in filamentous fungi.Kaplan O, Bezouška K, Malandra A, Veselá AB, Petříčková A, Felsberg J, Rinágelová A, Křen V, Martínková L2011 Feb20882316