Enzyme

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EC Tree
     3. Hydrolases
        3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
            3.5.99 In other compounds
ID:3.5.99.5
Description:2-aminomuconate deaminase.
Cath: 3.30.1330.40;

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.5.99.5
BRENDA Enzyme Link: BRENDA 3.5.99.5
KEGG Enzyme Link: KEGG3.5.99.5
BioCyc Enzyme Link: BioCyc 3.5.99.5
ExPASy Enzyme Link: ExPASy3.5.99.5
EC2PDB Enzyme Link: EC2PDB 3.5.99.5
ExplorEnz Enzyme Link: ExplorEnz 3.5.99.5
PRIAM enzyme-specific profiles Link: PRIAM 3.5.99.5
IntEnz Enzyme Link: IntEnz 3.5.99.5
MEDLINE Enzyme Link: MEDLINE 3.5.99.5
MSA:

3.5.99.5;

Phylogenetic Tree:

3.5.99.5;

Uniprot:
M-CSA:
RHEA:20996 (2Z,4E)-2-aminomuconate + H2O = (3E)-2-oxohex-3-enedioate + NH4(+)
RULE(radius=1) [*:1]-[CH;+0:2]=[CH;+0:3]-[CH;+0:4]=[C;H0;+0:5](-[*:6])-[NH2;+0:7].[OH2;+0:8]>>[*:1]-[CH2;+0:2]-[CH;+0:3]=[CH;+0:4]-[C;H0;+0:5](-[*:6])=[O;H0;+0:8].[NH3;+0:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Complete nucleotide sequence and functional analysis of the genes for 2-aminophenol metabolism from Pseudomonas sp. AP-3.Takenaka S, Murakami S, Kim YJ, Aoki K2000 Oct11081795
A novel 2-aminomuconate deaminase in the nitrobenzene degradation pathway of Pseudomonas pseudoalcaligenes JS45.He Z, Spain JC1998 May9573204
Studies of the catabolic pathway of degradation of nitrobenzene by Pseudomonas pseudoalcaligenes JS45: removal of the amino group from 2-aminomuconic semialdehyde.He Z, Spain JC1997 Dec9471964
Prokaryotic homologs of the eukaryotic 3-hydroxyanthranilate 3,4-dioxygenase and 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase in the 2-nitrobenzoate degradation pathway of Pseudomonas fluorescens strain KU-7.Muraki T, Taki M, Hasegawa Y, Iwaki H, Lau PC2003 Mar12620844