Enzyme

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     3. Hydrolases
        3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
            3.5.99 In other compounds
ID:3.5.99.9
Description:2-nitroimidazole nitrohydrolase.
Alternative Name: 2NI nitrohydrolase.
2NI denitrase.

3D structure

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References

External Links

UniProtKB Enzyme Link: UniProtKB 3.5.99.9
BRENDA Enzyme Link: BRENDA 3.5.99.9
KEGG Enzyme Link: KEGG3.5.99.9
BioCyc Enzyme Link: BioCyc 3.5.99.9
ExPASy Enzyme Link: ExPASy3.5.99.9
EC2PDB Enzyme Link: EC2PDB 3.5.99.9
ExplorEnz Enzyme Link: ExplorEnz 3.5.99.9
PRIAM enzyme-specific profiles Link: PRIAM 3.5.99.9
IntEnz Enzyme Link: IntEnz 3.5.99.9
MEDLINE Enzyme Link: MEDLINE 3.5.99.9
MSA:

3.5.99.9;

Phylogenetic Tree:

3.5.99.9;

Uniprot:
M-CSA:
RHEA:34271 2-nitroimidazole + H2O = 1,3-dihydro-2H-imidazol-2-one + H(+) + nitrite
RULE(radius=1) [*:1]=[N+;H0:2](-[*:3])-[c;H0;+0:4](:[*:5]):[n;H0;+0:6]:[*:7].[OH2;+0:8]>>[*:7]:[nH;+0:6]:[c;H0;+0:4](:[*:5])=[O;H0;+0:8].[*:1]=[N;H0;+0:2]-[*:3]
Reaction
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References

TitleAuthorsDatePubMed ID
Catabolic pathway for 2-nitroimidazole involves a novel nitrohydrolase that also confers drug resistance.Qu Y, Spain JC2011 Apr21244596