EC number:3.6.1.15
Enzyme
Download| EC Tree |
| 3. Hydrolases |
| 3.6 Acting on acid anhydrides |
| 3.6.1 In phosphorus-containing anhydrides |
| ID: | 3.6.1.15 | ||
|---|---|---|---|
| Description: | Nucleoside-triphosphate phosphatase. | ||
| Alternative Name: |
Nucleoside-triphosphatase. Nucleoside-5-triphosphate phosphohydrolase. Nucleoside triphosphate phosphohydrolase. Nucleoside triphosphate hydrolase. Nucleoside 5-triphosphatase. NTPase. | ||
| Prosite: | PDOC00952; | ||
| PDB: |
|
||
| Cath: | 1.10.10.870; 1.10.10.930; 1.10.1220.10; 1.10.1220.100; 1.10.260.110; 1.10.260.90; 1.10.287.1610; 1.10.8.970; 1.10.820.10; 1.20.1280.150; |
3D structure
Click one PDB to see exact 3D structure provided by NGL.
Note: Use your mouse to drag, rotate, and zoom in and out of the structure. Mouse-over to identify atoms and bonds. Mouse controls documentation.References
External Links
| UniProtKB Enzyme Link: | UniProtKB 3.6.1.15 |
| BRENDA Enzyme Link: | BRENDA 3.6.1.15 |
| KEGG Enzyme Link: | KEGG3.6.1.15 |
| BioCyc Enzyme Link: | BioCyc 3.6.1.15 |
| ExPASy Enzyme Link: | ExPASy3.6.1.15 |
| EC2PDB Enzyme Link: | EC2PDB 3.6.1.15 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.6.1.15 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.6.1.15 |
| IntEnz Enzyme Link: | IntEnz 3.6.1.15 |
| MEDLINE Enzyme Link: | MEDLINE 3.6.1.15 |
| RHEA:23680 | a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + H(+) + phosphate |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[OH2;+0:7]>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[OH;+0:7] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The major nucleoside triphosphatase in pea (Pisum sativum L.) nuclei and in rat liver nuclei share common epitopes also present in nuclear lamins. | Tong CG, Dauwalder M, Clawson GA, Hatem CL, Roux SJ | 1993 Mar | 7508630 |
| Lysosomal acid pyrophosphatase and acid phosphatase. | Brightwell R, Tappel AL | 1968 Mar 20 | 5661608 |
| Purification of nucleoside triphosphatases from pea seedling ribosomes. | Matsushita S, Raacke ID | 1968 Oct 29 | 4301913 |
| NMR structure and functional characterization of a human cancer-related nucleoside triphosphatase. | Placzek WJ, Almeida MS, Wüthrich K | 2007 Mar 30 | 17291528 |
| Thermophile-specific proteins: the gene product of aq_1292 from Aquifex aeolicus is an NTPase. | Klinger C, Rossbach M, Howe R, Kaufmann M | 2003 Sep 23 | 14503925 |
| PROPERTIES OF A SOLUBLE NUCLEOSIDE TRIPHOSPHATASE ACTIVITY IN MAMMALIAN LIVER. | LEWIS M, WEISSMAN S | 1965 Mar | 14320490 |