EC number:3.6.1.40

Enzyme

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EC Tree
     3. Hydrolases
        3.6 Acting on acid anhydrides
            3.6.1 In phosphorus-containing anhydrides
ID:3.6.1.40
Description:Guanosine-5'-triphosphate,3'-diphosphate diphosphatase.
Alternative Name: pppGpp 5'-phosphohydrolase.
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase.
Guanosine pentaphosphate phosphohydrolase.
Cath: 1.10.3210.10;

3D structure

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PDB

References

External Links

UniProtKB Enzyme Link: UniProtKB 3.6.1.40
BRENDA Enzyme Link: BRENDA 3.6.1.40
KEGG Enzyme Link: KEGG3.6.1.40
BioCyc Enzyme Link: BioCyc 3.6.1.40
ExPASy Enzyme Link: ExPASy3.6.1.40
EC2PDB Enzyme Link: EC2PDB 3.6.1.40
ExplorEnz Enzyme Link: ExplorEnz 3.6.1.40
PRIAM enzyme-specific profiles Link: PRIAM 3.6.1.40
IntEnz Enzyme Link: IntEnz 3.6.1.40
MEDLINE Enzyme Link: MEDLINE 3.6.1.40

EC number:3.6.1.40

MSA:

3.6.1.40;
Phylogenetic Tree:

3.6.1.40;
Uniprot:
M-CSA:
RHEA:13073 guanosine 3'-diphosphate 5'-triphosphate + H2O = guanosine 3',5'-bis(diphosphate) + phosphate
RULE(radius=1) [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[OH2;+0:7]>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[OH;+0:7]
Reaction
Core-to-Core No scaffolds atoms were exchanged as a result of the reaction

References

TitleAuthorsDatePubMed ID
Guanosine 5'-triphosphate, 3'-diphosphate 5'-phosphohydrolase. Purification and substrate specificity.Hara A, Sy J1983 Feb 106130093