EC number:3.6.1.41
Enzyme
Download| EC Tree |
| 3. Hydrolases |
| 3.6 Acting on acid anhydrides |
| 3.6.1 In phosphorus-containing anhydrides |
| ID: | 3.6.1.41 |
|---|---|
| Description: | Bis(5'-nucleosyl)-tetraphosphatase (symmetrical). |
| Alternative Name: |
Dinucleosidetetraphosphatase (symmetrical). Diadenosinetetraphosphatase (symmetrical). Diadenosine 5',5'''-P(1),P(4)-tetraphosphate pyrophosphohydrolase. Ap4A hydrolase. Ap(4)A hydrolase. |
| Cath: | 1.10.30.30; 1.20.1430.20; 3.30.428.10; 3.30.930.10; 3.40.50.80; 3.40.50.800; 3.60.21.10; 3.90.79.10; |
3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.6.1.41 |
| BRENDA Enzyme Link: | BRENDA 3.6.1.41 |
| KEGG Enzyme Link: | KEGG3.6.1.41 |
| BioCyc Enzyme Link: | BioCyc 3.6.1.41 |
| ExPASy Enzyme Link: | ExPASy3.6.1.41 |
| EC2PDB Enzyme Link: | EC2PDB 3.6.1.41 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.6.1.41 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.6.1.41 |
| IntEnz Enzyme Link: | IntEnz 3.6.1.41 |
| MEDLINE Enzyme Link: | MEDLINE 3.6.1.41 |
| RHEA:30527 | H2O + P(1),P(5)-bis(5'-adenosyl)pentaphosphate = ADP + ATP + 2 H(+) |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[OH2;+0:7]>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[OH;+0:7] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| The Nudix hydrolase Ndx1 from Thermus thermophilus HB8 is a diadenosine hexaphosphate hydrolase with a novel activity. | Iwai T, Kuramitsu S, Masui R | 2004 May 21 | 15024014 |
| RHEA:30203 | H2O + P(1),P(4)-bis(5'-guanosyl) tetraphosphate = 2 GDP + 2 H(+) |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[OH2;+0:7]>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[OH;+0:7] |
| Reaction |  |
| Core-to-Core |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Catabolism of diadenosine 5',5"'-P1,P4-tetraphosphate in procaryotes. Purification and properties of diadenosine 5',5"'-P1,P4-tetraphosphate (symmetrical) pyrophosphohydrolase from Escherichia coli K12. | Guranowski A, Jakubowski H, Holler E | 1983 Dec 25 | 6317672 |
| RHEA:24252 | H2O + P(1),P(4)-bis(5'-adenosyl)tetraphosphate = 2 ADP + 2 H(+) |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[OH2;+0:7]>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[OH;+0:7] |
| Reaction |  |
| Core-to-Core |