EC number:3.6.1.42
Enzyme
Download| EC Tree |
| 3. Hydrolases |
| 3.6 Acting on acid anhydrides |
| 3.6.1 In phosphorus-containing anhydrides |
| ID: | 3.6.1.42 | ||
|---|---|---|---|
| Description: | Guanosine-diphosphatase. | ||
| Alternative Name: |
GDPase. | ||
| Prosite: | PDOC00952; | ||
| PDB: |
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3D structure
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External Links
| UniProtKB Enzyme Link: | UniProtKB 3.6.1.42 |
| BRENDA Enzyme Link: | BRENDA 3.6.1.42 |
| KEGG Enzyme Link: | KEGG3.6.1.42 |
| BioCyc Enzyme Link: | BioCyc 3.6.1.42 |
| ExPASy Enzyme Link: | ExPASy3.6.1.42 |
| EC2PDB Enzyme Link: | EC2PDB 3.6.1.42 |
| ExplorEnz Enzyme Link: | ExplorEnz 3.6.1.42 |
| PRIAM enzyme-specific profiles Link: | PRIAM 3.6.1.42 |
| IntEnz Enzyme Link: | IntEnz 3.6.1.42 |
| MEDLINE Enzyme Link: | MEDLINE 3.6.1.42 |
| RHEA:22156 | GDP + H2O = GMP + H(+) + phosphate |
| RULE(radius=1) | [*:1]-[O;H0;+0:2]-[P;H0;+0:3](=[*:4])(-[*:5])-[*:6].[OH2;+0:7]>>[*:1]-[OH;+0:2].[*:4]=[P;H0;+0:3](-[*:5])(-[*:6])-[OH;+0:7] |
| Reaction |  |
| Core-to-Core | No scaffolds atoms were exchanged as a result of the reaction |
References
| Title | Authors | Date | PubMed ID |
|---|---|---|---|
| Purification and characterization of a guanosine diphosphatase activity from calf liver microsomal salt wash proteins. | Raychaudhuri P, Ghosh S, Maitra U | 1985 Jul 15 | 2989286 |
| The ER UDPase ENTPD5 promotes protein N-glycosylation, the Warburg effect, and proliferation in the PTEN pathway. | Fang M, Shen Z, Huang S, Zhao L, Chen S, Mak TW, Wang X | 2010 Nov 24 | 21074248 |
| Characterization of gdp1+ as encoding a GDPase in the fission yeast Schizosaccharomyces pombe. | Sánchez R, Franco A, Gacto M, Notario V, Cansado J | 2003 Nov 7 | 14612233 |
| The UDPase activity of the Kluyveromyces lactis Golgi GDPase has a role in uridine nucleotide sugar transport into Golgi vesicles. | Lopez-Avalos MD, Uccelletti D, Abeijon C, Hirschberg CB | 2001 May | 11425802 |